Pancreatic cancer in chronic pancreatitis: pathogenesis and diagnostic approach

G Le Cosquer, C Maulat, B Bournet, P Cordelier… - Cancers, 2023 - mdpi.com
Simple Summary Chronic alcoholic pancreatitis displays a cumulative risk of pancreatic
cancer estimated at 4% after 15 to 20 years, this risk being higher for hereditary pancreatitis …

AGA white paper: optimizing endoscopic ultrasound–guided tissue acquisition and future directions

S Wani, VR Muthusamy, CM McGrath… - Clinical …, 2018 - cghjournal.org
Technology (CGIT) conducted a 1-day workshop to discuss endoscopic ultrasound–guided
tissue acquisition (EUS-TA), focusing on the variables that impact outcomes associated with …

A multicenter randomized trial comparing a 25-gauge EUS fine-needle aspiration device with a 20-gauge EUS fine-needle biopsy device

PA van Riet, A Larghi, F Attili, G Rindi… - Gastrointestinal …, 2019 - Elsevier
Background and Aims Several studies have compared EUS-guided FNA with fine-needle
biopsy (FNB), but none have proven superiority. We performed a multicenter randomized …

MicroRNAs as indicators of malignancy in pancreatic ductal adenocarcinoma (PDAC) and cystic pancreatic lesions

C Prinz, L Fehring, R Frese - Cells, 2022 - mdpi.com
The dysregulation of microRNAs has recently been associated with cancer development
and progression in pancreatic ductal adenocarcinoma (PDAC) and cystic pancreatic lesions …

S100 proteins in pancreatic cancer: current knowledge and future perspectives

Y Wu, Q Zhou, F Guo, M Chen, X Tao, D Dong - Frontiers in Oncology, 2021 - frontiersin.org
Pancreatic cancer (PC) is a highly malignant tumor occurring in the digestive system.
Currently, there is a lack of specific and effective interventions for PC; thus, further …

[HTML][HTML] Molecular alterations in pancreatic tumors

M Visani, G Acquaviva, A De Leo, V Sanza… - World journal of …, 2021 - ncbi.nlm.nih.gov
Genetic alterations in pancreatic tumors can usually be classified in:(1) Mutational activation
of oncogenes;(2) Inactivation of tumor suppressor genes; and (3) Inactivation of genome …

The role of endoscopic ultrasound in pancreatic cancer screening

MS Bhutani, P Koduru, V Joshi, P Saxena… - Endoscopic …, 2016 - journals.lww.com
Pancreatic cancer (PC) is a highly lethal cancer. Despite a significant advancement in
cancer treatment, the mortality rate of PC is nearly identical to the incidence rates. Early …

Pancreatic cancer organoids for determining sensitivity to bromodomain and extra-terminal inhibitors (BETi)

B Bian, NA Juiz, O Gayet, M Bigonnet… - Frontiers in …, 2019 - frontiersin.org
Pancreatic ductal adenocarcinoma (PDAC) is a heterogeneous disease, therefore
stratification of patients is essential to predict their responses to therapies and to choose the …

Fully automated PCR detection of KRAS mutations on pancreatic endoscopic ultrasound fine-needle aspirates

D De Biase, C de Luca, G Gragnano, M Visani… - Journal of Clinical …, 2016 - jcp.bmj.com
Aims In cystic and solid pancreatic lesions, KRAS mutational status refines the diagnosis of
uncertain endoscopic ultrasound (EUS) aspirates. This test should have a fast turnaround …

Digital PCR improves mutation analysis in pancreas fine needle aspiration biopsy specimens

S Sho, CM Court, S Kim, DR Braxton, S Hou… - PLoS …, 2017 - journals.plos.org
Applications of precision oncology strategies rely on accurate tumor genotyping from
clinically available specimens. Fine needle aspirations (FNA) are frequently obtained in …