Effectiveness of three calcitonin gene-related peptide monoclonal antibodies for migraine: a 12-month, single-center, observational real-world study in Japan

K Suzuki, S Suzuki, T Shiina, M Tatsumoto… - …, 2023 - journals.sagepub.com
Background Real-world data on the effectiveness of calcitonin gene-related peptide
monoclonal antibodies (CGRP mAbs) in migraine patients are needed. Methods We …

[HTML][HTML] The causal effects between gut microbiota and hemorrhagic stroke: a bidirectional two-sample Mendelian randomization study

Y Shen, H Liu, X Meng, A Gao, Y Liu, W Ma… - Frontiers in …, 2023 - frontiersin.org
Background Recent studies have suggested that the composition of gut microbiota (GM)
may change after intracerebral hemorrhage. However, the causal inference of GM and …

[HTML][HTML] The global burden of motor neuron disease: an analysis of the 2019 global burden of disease study

J Park, JE Kim, TJ Song - Frontiers in Neurology, 2022 - frontiersin.org
Up-to-date, accurate information on the disease burden of motor neuron disease (MND) is
the cornerstone for evidence-based resource allocation and healthcare planning. We aimed …

Contemporary antiplatelet and anticoagulant therapies for secondary stroke prevention: a narrative review of current literature and guidelines

K Bhatia, LM Ladd, KH Carr, M Di Napoli… - Current Neurology and …, 2023 - Springer
Abstract Purpose of Review Stroke is a leading cause of death and disability worldwide. The
annual incidence of new or recurrent stroke is approximately 795,000 cases per year in the …

Small molecules as modulators of regulated cell death against ischemia/reperfusion injury

DQ Chen, Y Guo, X Li, GQ Zhang… - Medicinal research …, 2022 - Wiley Online Library
Ischemia/reperfusion (IR) injury contributes to disability and mortality worldwide. Due to the
complicated mechanisms and lack of proper therapeutic targets, few interventions are …

Tuberculosis and risk of ischemic stroke: a nationwide cohort study

HR Lee, JE Yoo, H Choi, K Han, JH Jung, J Park… - Stroke, 2022 - Am Heart Assoc
Background: Conflicting results exist regarding the risk of ischemic stroke in tuberculosis
survivors. We aimed to estimate the risk of ischemic stroke using a nationwide population …

Vildagliptin improves neurological function by inhibiting apoptosis and ferroptosis following intracerebral hemorrhage in mice

Y Zhang, X Zhang, VW Yong, M Xue - Neuroscience Letters, 2022 - Elsevier
Intracerebral hemorrhage (ICH) is a fatal health problem which lacks effective treatment. The
apoptosis caused by hematoma constituents, and the ferroptosis due to iron overload, are …

[HTML][HTML] Comparison of presentation and prognosis of Takayasu arteritis with or without stroke or transient ischemic attack—a retrospective cohort study

DP Misra, U Rathore, P Mishra, K Singh, DR Thakare… - Life, 2022 - mdpi.com
Takayasu arteritis (TAK) could cause a stroke or transient ischemic attack (TIA) in young
individuals due to inflammatory vascular occlusion or intracerebral hemorrhage. We …

[HTML][HTML] Infectious mononucleosis is associated with an increased incidence of multiple sclerosis: Results from a cohort study of 32,116 outpatients in Germany

SH Loosen, C Doege, SG Meuth, T Luedde… - Frontiers in …, 2022 - frontiersin.org
Background The pathogenesis of multiple sclerosis (MS) has not yet been fully uncovered.
There is increasing evidence that Epstein-Barr-Virus (EBV) infection, which affects over 90 …

[HTML][HTML] Targeted suppression of mTORC2 reduces seizures across models of epilepsy

J Okoh, J Mays, A Bacq, JA Oses-Prieto… - Nature …, 2023 - nature.com
Epilepsy is a neurological disorder that poses a major threat to public health.
Hyperactivation of mTOR complex 1 (mTORC1) is believed to lead to abnormal network …