Environmental determinants of cardiovascular disease: lessons learned from air pollution

SG Al-Kindi, RD Brook, S Biswal… - Nature Reviews …, 2020 - nature.com
Air pollution is well recognized as a major risk factor for chronic non-communicable
diseases and has been estimated to contribute more to global morbidity and mortality than …

DNA methylation: a potential mediator between air pollution and metabolic syndrome

P Poursafa, Z Kamali, E Fraszczyk, HM Boezen… - Clinical …, 2022 - Springer
Given the global increase in air pollution and its crucial role in human health, as well as the
steep rise in prevalence of metabolic syndrome (MetS), a better understanding of the …

Air pollution and DNA methylation in adults: a systematic review and meta-analysis of observational studies

Y Wu, R Qie, M Cheng, Y Zeng, S Huang, C Guo… - Environmental …, 2021 - Elsevier
This systematic review and meta-analysis aimed to investigate the association between air
pollution and DNA methylation in adults from published observational studies. PubMed …

Genome-wide DNA methylation analysis reveals significant impact of long-term ambient air pollution exposure on biological functions related to mitochondria and …

M Wang, J Zhao, Y Wang, Y Mao, X Zhao… - Environmental …, 2020 - Elsevier
Exposure to long-term ambient air pollution is believed to have adverse effects on human
health. However, the mechanisms underlying these impacts are poorly understood. DNA …

Genome-wide DNA methylation in peripheral blood and long-term exposure to source-specific transportation noise and air pollution: the SAPALDIA study

IC Eze, A Jeong, E Schaffner, FI Rezwan… - Environmental …, 2020 - ehp.niehs.nih.gov
Background: Few epigenome-wide association studies (EWAS) on air pollutants exist, and
none have been done on transportation noise exposures, which also contribute to …

Long-term exposure to ambient fine particulate components and leukocyte epigenome-wide DNA Methylation in older men: the Normative Aging Study

C Wang, H Amini, Z Xu, AA Peralta, MD Yazdi… - Environmental …, 2023 - Springer
Background Epigenome-wide association studies of ambient fine particulate matter (PM2. 5)
have been reported. However, few have examined PM2. 5 components (PMCs) and sources …

Association of glyphosate exposure with blood DNA methylation in a cross-sectional study of postmenopausal women

RM Lucia, WL Huang, KV Pathak… - Environmental …, 2022 - ehp.niehs.nih.gov
Background: Glyphosate is the most commonly used herbicide in the world and is purported
to have a variety of health effects, including endocrine disruption and an elevated risk of …

[HTML][HTML] Aryl hydrocarbon receptor as a DNA methylation reader in the stress response pathway

W Habano, T Miura, J Terashima, S Ozawa - Toxicology, 2022 - Elsevier
The aryl hydrocarbon receptor (AhR) mediates various cellular responses upon exposure to
exogenous and endogenous stress factors. In these responses, AhR plays a dual role as a …

Methylomic, Proteomic, and Metabolomic Correlates of Traffic-Related Air Pollution in the Context of Cardiorespiratory Health: A Systematic Review, Pathway Analysis …

C Casella, F Kiles, C Urquhart, DS Michaud, K Kirwa… - Toxics, 2023 - mdpi.com
A growing body of literature has attempted to characterize how traffic-related air pollution
(TRAP) affects molecular and subclinical biological processes in ways that could lead to …

Gaseous air pollutants and DNA methylation in a methylome-wide association study of an ethnically and environmentally diverse population of US adults

KM Holliday, R Gondalia, A Baldassari, AE Justice… - Environmental …, 2022 - Elsevier
Epigenetic mechanisms may underlie air pollution-health outcome associations. We
estimated gaseous air pollutant-DNA methylation (DNAm) associations using twelve …