Most circular RNAs are produced from the back-splicing of exons of precursor mRNAs.
Recent technological advances have in part overcome problems with their circular …

Over the past decade, circular RNAs (circRNAs) have emerged as a large class of primarily
non-coding RNA molecules, many of which have key roles in cancer development and …

Covalently closed, single-stranded circular RNAs can be produced from viral RNA genomes
as well as from the processing of cellular housekeeping noncoding RNAs and precursor …

To date, thousands of highly abundant and conserved single-stranded RNA molecules
shaped into ring structures (circRNAs) have been identified. CircRNAs are multifunctional …

Exon back-splicing-generated circular RNAs, as a group, can suppress double-stranded
RNA (dsRNA)-activated protein kinase R (PKR) in cells. We have sought to synthesize …

Psoriasis is a common inflammatory skin disease involving interactions between
keratinocytes and immune cells that significantly affects the quality of life. It is characterized …

Psoriasis (PSO) and atopic dermatitis (AD) were once considered to be mutually exclusive
diseases, but gradually regarded as a spectrum of disease. Shared genetic loci of both …

Gene expression in eukaryotic cells is a complex process encompassing several layers of
regulation at the transcriptional and post-transcriptional levels. At the post-transcriptional …

Circular RNAs (circRNAs) as a new class of non-coding RNAs (ncRNAs) play role in gene
regulation in multicellular organisms via various interactions with nucleic acids, proteins and …

Stringent spatiotemporal regulation of the wound healing process involving multiple cell
types is associated with epigenetic mechanisms of gene regulation, such as DNA …