The cytokine storm in COVID-19: An overview of the involvement of the chemokine/chemokine-receptor system
In 2019–2020 a new coronavirus named SARS-CoV-2 was identified as the causative agent
of a several acute respiratory infection named COVID-19, which is causing a worldwide …
of a several acute respiratory infection named COVID-19, which is causing a worldwide …
Overview of immune response during SARS-CoV-2 infection: lessons from the past
After the 1918 flu pandemic, the world is again facing a similar situation. However, the
advancement in medical science has made it possible to identify that the novel infectious …
advancement in medical science has made it possible to identify that the novel infectious …
[HTML][HTML] Detection of SARS-CoV-2-specific humoral and cellular immunity in COVID-19 convalescent individuals
L Ni, F Ye, ML Cheng, Y Feng, YQ Deng, H Zhao… - Immunity, 2020 - cell.com
Summary The World Health Organization has declared SARS-CoV-2 virus outbreak a
worldwide pandemic. However, there is very limited understanding on the immune …
worldwide pandemic. However, there is very limited understanding on the immune …
Type 1 interferons as a potential treatment against COVID-19
Type 1 interferons have a broad antiviral activity in vitro and are currently evaluated in a
clinical trial to treat MERS-CoV. In this review, we discuss preliminary data concerning the …
clinical trial to treat MERS-CoV. In this review, we discuss preliminary data concerning the …
Critical determinants of cytokine storm and type I interferon response in COVID-19 pathogenesis
S Ramasamy, S Subbian - Clinical microbiology reviews, 2021 - Am Soc Microbiol
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus
disease 2019 (COVID-19), a rapidly evolving pandemic worldwide with at least 68 million …
disease 2019 (COVID-19), a rapidly evolving pandemic worldwide with at least 68 million …
A comprehensive review of viral characteristics, transmission, pathophysiology, immune response, and management of SARS-CoV-2 and COVID-19 as a basis for …
COVID-19 emerged from China in December 2019 and during 2020 spread to every
continent including Antarctica. The coronavirus, SARS-CoV-2, has been identified as the …
continent including Antarctica. The coronavirus, SARS-CoV-2, has been identified as the …
Risk factors for mortality in patients with COVID-19 in New York City
Abstract Background New York City emerged as an epicenter of the coronavirus disease
2019 (COVID-19) pandemic. Objective To describe the clinical characteristics and risk …
2019 (COVID-19) pandemic. Objective To describe the clinical characteristics and risk …
Severely ill patients with COVID-19 display impaired exhaustion features in SARS-CoV-2–reactive CD8+ T cells
The molecular properties of CD8+ T cells that respond to SARS-CoV-2 infection are not fully
known. Here, we report on the single-cell transcriptomes of> 80,000 virus-reactive CD8+ T …
known. Here, we report on the single-cell transcriptomes of> 80,000 virus-reactive CD8+ T …
Type I interferon susceptibility distinguishes SARS-CoV-2 from SARS-CoV
KG Lokugamage, A Hage, M de Vries… - Journal of …, 2020 - Am Soc Microbiol
ABSTRACT SARS-CoV-2, a novel coronavirus (CoV) that causes COVID-19, has recently
emerged causing an ongoing outbreak of viral pneumonia around the world. While distinct …
emerged causing an ongoing outbreak of viral pneumonia around the world. While distinct …
[HTML][HTML] Chemokines and chemokine receptors during COVID-19 infection
Chemokines are crucial inflammatory mediators needed during an immune response to
clear pathogens. However, their excessive release is the main cause of hyperinflammation …
clear pathogens. However, their excessive release is the main cause of hyperinflammation …