Abstract N6-methyladenosine (m 6 A) RNA methylation is the most abundant form of mRNA
modification in eukaryotes and is at the front line of biological and biomedical research. This …

Abstract Adenosine-to-inosine (A-to-I) editing of RNA, catalyzed by adenosine deaminase
acting on RNA (ADAR) enzymes, is a prevalent RNA modification in mammals. It has been …

Here, in a multi-ancestry genome-wide association study meta-analysis of kidney cancer
(29,020 cases and 835,670 controls), we identified 63 susceptibility regions (50 novel) …

YY1 affects tumorigenesis and metastasis in multiple ways. However, the function of YY1
and the potential mechanisms through which it operates in gastric cancer (GC) progression …

Integrin receptors for the extracellular matrix activate intracellular signaling pathways that
are critical for tissue development, homeostasis, and regeneration/repair, and their loss or …

The advent of high-throughput sequencing uncovered that our genome is pervasively
transcribed into RNAs that are seemingly not translated into proteins. It was also found that …

Genomic information stored in the DNA is transcribed to the mRNA and translated to
proteins. The 3′ untranslated regions (3′ UTRs) of the mRNA serve pivotal roles in post …

The anticancer drugs cis-diamminedichloridoplatinum (II)(cisplatin) and oxaliplatin are
commonly used to treat patients with a number of cancers including gastrointestinal cancer …

Background A growing body of evidence indicates that oxidative stress, high levels of
reactive oxygen species (ROS), is implicated in the pathogenesis of breast cancer (BC) …

To fully understand gene regulation, it is necessary to have a thorough understanding of
both the transcriptome and the enzymatic and RNA-binding activities that shape it. While …