The effect of photopolymerization on stem cells embedded in hydrogels

NE Fedorovich, MH Oudshoorn, D van Geemen… - Biomaterials, 2009 - Elsevier
Photopolymerizable hydrogels, formed by UV-exposure of photosensitive polymers in the
presence of photoinitiators, are widely used materials in tissue engineering research …

Microfluidic trends in drug screening and drug delivery

J Feng, J Neuzil, A Manz, C Iliescu, P Neuzil - TrAC Trends in Analytical …, 2023 - Elsevier
The low probability of a drug candidate's clinical success, the time consumed and the high
cost of bringing a drug from concept to market emphasizes the need for new approaches to …

Microengineered platforms for cell mechanobiology

DH Kim, PK Wong, J Park… - Annual review of …, 2009 - annualreviews.org
Mechanical forces play important roles in the regulation of various biological processes at
the molecular and cellular level, such as gene expression, adhesion, migration, and cell …

Engineering microscale cellular niches for three-dimensional multicellular co-cultures

CP Huang, J Lu, H Seon, AP Lee, LA Flanagan… - Lab on a Chip, 2009 - pubs.rsc.org
Modeling the in vivo microenvironment typically involves placing cells in a three-
dimensional (3D) extracellular matrix (ECM) in physiologically relevant context with respect …

Hydrogels as extracellular matrices for skeletal tissue engineering: state-of-the-art and novel application in organ printing

NE Fedorovich, J Alblas, JR de Wijn… - Tissue …, 2007 - liebertpub.com
Organ printing, a novel approach in tissue engineering, applies layered computer-driven
deposition of cells and gels to create complex 3-dimensional cell-laden structures. It shows …

A practical guide to microfluidic perfusion culture of adherent mammalian cells

L Kim, YC Toh, J Voldman, H Yu - Lab on a Chip, 2007 - pubs.rsc.org
Culturing cells at microscales allows control over microenvironmental cues, such as cell–cell
and cell–matrix interactions; the potential to scale experiments; the use of small culture …

Biomatrices and biomaterials for future developments of bioprinting and biofabrication

M Nakamura, S Iwanaga, C Henmi, K Arai… - …, 2010 - iopscience.iop.org
The next step beyond conventional scaffold-based tissue engineering is cell-based direct
biofabrication techniques. In industrial processes, various three-dimensional (3D) prototype …

3D bioprinting: improving in vitro models of metastasis with heterogeneous tumor microenvironments

JL Albritton, JS Miller - Disease models & mechanisms, 2017 - journals.biologists.com
Even with many advances in treatment over the past decades, cancer still remains a leading
cause of death worldwide. Despite the recognized relationship between metastasis and …

Fabrication of 3D hepatic tissues by additive photopatterning of cellular hydrogels

VL Tsang, AA Chen, LM Cho, KD Jadin… - The FASEB …, 2007 - Wiley Online Library
We have fabricated a hepatic tissue construct using a multilayer photopatterning platform for
embedding cells in hydrogels of complex architecture. We first explored the potential of …

Design, fabrication and characterization of drug delivery systems based on lab-on-a-chip technology

NT Nguyen, SAM Shaegh, N Kashaninejad… - Advanced drug delivery …, 2013 - Elsevier
Lab-on-a-chip technology is an emerging field evolving from the recent advances of micro-
and nanotechnologies. The technology allows the integration of various components into a …