The micro-environment in which stem cells reside regulates their fate, and synthetic
materials have recently been designed to emulate these regulatory processes for various …

Protein dielectrophoresis (DEP) has the potential to play an important role as a
manipulation, fractionation, preconcentration, and separation method in bioanalysis and as …

Tissue-engineered therapies for liver failure offer the potential to augment or replace whole
organ transplantation; however, fabrication of hepatic tissue poses unique challenges …

Complex tissues contain multiple cell types that are hierarchically organized within
morphologically and functionally distinct compartments. Construction of engineered tissues …

High throughput experiments can be used to spatially and temporally investigate the many
factors that regulate cell differentiation. We have developed a micro-bioreactor array (MBA) …

Glioblastoma the most aggressive form of brain cancer, comprises a complex mixture of
tumor cells and nonmalignant stromal cells, including neurons, astrocytes, microglia …

The concept of using stem cells as self-renewing sources of healthy cells in regenerative
medicine has existed for decades, but most applications have yet to achieve clinical …

BACKGROUND: Inside the body, cells lie in direct contact or in close proximity to other cell
types in a tightly controlled architecture that often regulates the resulting tissue function …

Accurate modeling of the cellular microenvironment is important for improving studies of cell
biology in vitro. Here, we demonstrate a flexible method for creating a cellular …

3D microfluidic cell culture systems offer a biologically relevant model to conduct micro-
scale mammalian cell-based research and applications. Various natural and synthetic …