[HTML][HTML] Neuroprotection in glaucoma: mechanisms beyond intraocular pressure lowering

JR Tribble, F Hui, H Quintero, S El Hajji, K Bell… - Molecular aspects of …, 2023 - Elsevier
Glaucoma is a common, complex, multifactorial neurodegenerative disease characterized
by progressive dysfunction and then loss of retinal ganglion cells, the output neurons of the …

[HTML][HTML] Primary open angle glaucoma and vascular risk factors: a review of population based studies from 1990 to 2019

A Grzybowski, M Och, P Kanclerz, C Leffler… - Journal of clinical …, 2020 - mdpi.com
Glaucoma is one of the leading causes of blindness worldwide, and as the proportion of
those over age 40 increases, so will the prevalence of glaucoma. The pathogenesis of …

[HTML][HTML] A novel hybrid approach based on deep CNN to detect glaucoma using fundus imaging

R Mahum, SU Rehman, OD Okon, A Alabrah, T Meraj… - Electronics, 2021 - mdpi.com
Glaucoma is one of the eye diseases stimulated by the fluid pressure that increases in the
eyes, damaging the optic nerves and causing partial or complete vision loss. As Glaucoma …

Association between diabetes, diabetic retinopathy, and glaucoma

Y Li, W Mitchell, T Elze, N Zebardast - Current Diabetes Reports, 2021 - Springer
Abstract Purpose of Review The strength of the relationship between diabetes, diabetic
retinopathy (DR), and glaucoma remains controversial. We review evidence supporting and …

[HTML][HTML] Risk of cataract and glaucoma among older persons with diabetes in India: a cross-sectional study based on LASI, Wave-1

J Khan, S Shaw - Scientific Reports, 2023 - nature.com
Abstract According to the International Diabetes Federation-2019 estimates, India is home to
77 million diabetic individuals which is projected to grow up to 147.2 million by 2045 …

Insulin signalling promotes dendrite and synapse regeneration and restores circuit function after axonal injury

J Agostinone, L Alarcon-Martinez, C Gamlin, WQ Yu… - Brain, 2018 - academic.oup.com
Dendrite pathology and synapse disassembly are critical features of chronic
neurodegenerative diseases. In spite of this, the capacity of injured neurons to regenerate …

Insulin restores retinal ganglion cell functional connectivity and promotes visual recovery in glaucoma

S El Hajji, Y Shiga, N Belforte, YC Solorio, O Tastet… - Science …, 2024 - science.org
Dendrite pathology and synaptic loss result in neural circuit dysfunction, a common feature
of neurodegenerative diseases. There is a lack of strategies that target dendritic and …

[HTML][HTML] Oxidative stress and the role of NADPH oxidase in glaucoma

JC Fan Gaskin, MH Shah, EC Chan - Antioxidants, 2021 - mdpi.com
Glaucoma is characterised by loss of retinal ganglion cells, and their axons and many
pathophysiological processes are postulated to be involved. It is increasingly understood …

[HTML][HTML] Mendelian randomization analyses in ocular disease: a powerful approach to causal inference with human genetic data

J Li, C Li, Y Huang, P Guan, D Huang, H Yu… - Journal of Translational …, 2022 - Springer
Ophthalmic epidemiology is concerned with the prevalence, distribution and other factors
relating to human eye disease. While observational studies cannot avoid confounding …

[HTML][HTML] Glaucoma: from pathogenic mechanisms to retinal glial cell response to damage

JA Fernández-Albarral, AI Ramírez… - Frontiers in Cellular …, 2024 - frontiersin.org
Glaucoma is a neurodegenerative disease of the retina characterized by the irreversible loss
of retinal ganglion cells (RGCs) leading to visual loss. Degeneration of RGCs and loss of …