Role of sex hormone-binding globulin in the free hormone hypothesis and the relevance of free testosterone in androgen physiology
N Narinx, K David, J Walravens, P Vermeersch… - Cellular and Molecular …, 2022 - Springer
According to the free hormone hypothesis, biological activity of a certain hormone is best
reflected by free rather than total hormone concentrations. A crucial element in this theory is …
reflected by free rather than total hormone concentrations. A crucial element in this theory is …
Reference ranges and determinants of testosterone, dihydrotestosterone, and estradiol levels measured using liquid chromatography-tandem mass spectrometry in a …
BB Yeap, H Alfonso, SAP Chubb… - The Journal of …, 2012 - academic.oup.com
Context: Testosterone (T) levels decline with increasing age. Controversy exists over the
threshold for classifying T as low vs. normal in older men. The relevance of assessing …
threshold for classifying T as low vs. normal in older men. The relevance of assessing …
Effect of testosterone replacement on response to sildenafil citrate in men with erectile dysfunction: a parallel, randomized trial
M Spitzer, S Basaria, TG Travison… - Annals of internal …, 2012 - acpjournals.org
This article has been corrected. The original version (PDF) is appended to this article as a
supplement. Background: Erectile dysfunction and low testosterone levels frequently occur …
supplement. Background: Erectile dysfunction and low testosterone levels frequently occur …
Effect of testosterone replacement therapy on sexual function and hypogonadal symptoms in men with hypogonadism
KM Pencina, TG Travison… - The Journal of …, 2024 - academic.oup.com
Context Few long-term randomized trials have evaluated the efficacy of testosterone
replacement therapy (TRT) in improving sexual function and hypogonadal symptoms in men …
replacement therapy (TRT) in improving sexual function and hypogonadal symptoms in men …
Sex hormone therapy and tenofovir diphosphate concentration in dried blood spots: primary results of the interactions between antiretrovirals and transgender …
RM Grant, M Pellegrini, PA Defechereux… - Clinical Infectious …, 2021 - academic.oup.com
Background Sex hormone and preexposure prophylaxis (PrEP) drug interactions among
transgender women (TGW), transgender men (TGM), and cisgender men (CGM) are not fully …
transgender women (TGW), transgender men (TGM), and cisgender men (CGM) are not fully …
Testosterone replacement therapy: for whom, when and how?
CP Tsametis, AM Isidori - Metabolism, 2018 - Elsevier
The finding of low circulating testosterone level in men is relatively frequent. The symptoms
of hypogonadism are very frequent in the aging men. However, the diagnosis of …
of hypogonadism are very frequent in the aging men. However, the diagnosis of …
The future of sperm: a biovariability framework for understanding global sperm count trends
The past 50 years have seen heated debate in the reproductive sciences about global
trends in human sperm count. In 2017, Levine and colleagues published the largest and …
trends in human sperm count. In 2017, Levine and colleagues published the largest and …
Effects of testosterone treatment on body fat and lean mass in obese men on a hypocaloric diet: a randomised controlled trial
M Ng Tang Fui, LA Prendergast, P Dupuis, M Raval… - BMC medicine, 2016 - Springer
Background Whether testosterone treatment has benefits on body composition over and
above caloric restriction in men is unknown. We hypothesised that testosterone treatment …
above caloric restriction in men is unknown. We hypothesised that testosterone treatment …
Androgens, aging, and prostate health
K Welén, JE Damber - Reviews in Endocrine and Metabolic Disorders, 2022 - Springer
Due to late onset hypogonadism (LOH), there is an increased usage of testosterone
replacement therapy (TRT) in the aging male population. Since prostate is a target organ for …
replacement therapy (TRT) in the aging male population. Since prostate is a target organ for …
The safety, pharmacokinetics, and effects of LGD-4033, a novel nonsteroidal oral, selective androgen receptor modulator, in healthy young men
S Basaria, L Collins, EL Dillon, K Orwoll… - … Series A: Biomedical …, 2013 - academic.oup.com
Background. Concerns about potential adverse effects of testosterone on prostate have
motivated the development of selective androgen receptor modulators that display tissue …
motivated the development of selective androgen receptor modulators that display tissue …