EMAS position statement: Testosterone replacement therapy in the aging male‏‎

C Dimopoulou, I Ceausu, H Depypere, I Lambrinoudaki… - Maturitas, 2016 - Elsevier
Introduction Late-onset hypogonadism (LOH) represents a common clinical entity in aging
males, characterized by the presence of symptoms (most usually of a sexual nature, such as …

The laboratory diagnosis of testosterone deficiency

DA Paduch, RE Brannigan, EF Fuchs, ED Kim… - Urology, 2014 - Elsevier
The evaluation and treatment of hypogonadal men has become an important part of urologic
practice. Fatigue, loss of libido, and erectile dysfunction are commonly reported, but …

[PDF][PDF] Benefits and risks of testosterone treatment of older men with hypogonadism

FF Galbiati, AL Goldman, A Gattu, EC Guzelce… - Urologic Clinics of North …, 2022 - Elsevier
Total and free testosterone levels decline in men with advancing age due to defects at all
levels of the hypothalamic-pituitary-testicular axis. Age-related decline in total and free …

Free testosterone: pumping up the tires or ending the free ride?

DJ Handelsman - Endocrine reviews, 2017 - academic.oup.com
The review by Goldman et al.() is a strong restatement of the free hormone hypothesis
(FHH) with its contingent focus on measurement of so-called “free” testosterone (FT). The …

Sex in sport

DL Coleman - Law & Contemp. Probs., 2017 - HeinOnline
Sex classifications that sort males from females remain pervasive even as antidiscrimination
law designed to achieve equality for females has chipped away at their subordinating …

[PDF][PDF] Epidemiology of male hypogonadism

A Thirumalai, BD Anawalt - Endocrinology and metabolism clinics of North …, 2022 - Elsevier
The best available evidence indicates that the most common endogenous pathologic cause
of hypogonadism is Klinefelter syndrome (affecting up to∼ 0.2% of the male population) …

Treating exercise-associated low testosterone and its related symptoms

DR Hooper, AS Tenforde… - The Physician and …, 2018 - Taylor & Francis
ABSTRACT The Exercise-Hypogonadal Male Condition (EHMC) has been described to
occur in athletes who experience low serum testosterone and associated symptoms. While …

[HTML][HTML] APHRODITE criteria: addressing male patients with hypogonadism and/or infertility owing to altered idiopathic testicular function

SC Esteves, P Humaidan, FM Ubaldi, C Alviggi… - Reproductive …, 2024 - Elsevier
Research question Can a novel classification system of the infertile male–'APHRODITE'(
Addressing male Patients with Hypogonadism and/or infeRtility Owing to altereD, Idiopathic …

[HTML][HTML] TRPM8-androgen receptor association within lipid rafts promotes prostate cancer cell migration

GP Grolez, DV Gordiendko, M Clarisse… - Cell death & …, 2019 - nature.com
In prostate carcinogenesis, androgens are known to control the expression of the transient
receptor potential melastatin 8 (TRPM8) protein via activation of androgen receptor (AR) …

Sildenafil increases serum testosterone levels by a direct action on the testes

M Spitzer, S Bhasin, TG Travison, MN Davda… - …, 2013 - Wiley Online Library
Summary Phosphodiesterase‐5‐inhibitors, such as sildenafil, increase intracavernosal
cyclic guanosine monophosphate levels, which results in corporal smooth muscle relaxation …