• Early symptoms of brain tumours in adults are non-specific, and patients may present
multiple times to primary care services before they are referred for investigation. Look for …

Cancer cells can organize and communicate in functional networks. Similarly to other
networks in biology and sociology, these can be highly relevant for growth and resilience. In …

Seizures are a frequent pathophysiological feature of malignant glioma. Recent studies
implicate peritumoral synaptic dysregulation as a driver of brain hyperactivity and tumor …

Brain tumors represent the second most frequent etiology in patients with focal seizure onset
before 18 years of age and submitted to epilepsy surgery. Hence, this category of brain …

Glioblastoma is a universally lethal form of brain cancer that exhibits an array of
pathophysiological phenotypes, many of which are mediated by interactions with the …

Experience sculpts brain structure and function. Activity-dependent modulation of the
myelinated infrastructure of the nervous system has emerged as a dimension of adaptive …

Abstract Objective To update the 2000 American Academy of Neurology (AAN) practice
parameter on anticonvulsant prophylaxis in patients with newly diagnosed brain tumors …

Diffuse low-grade gliomas are highly epileptogenic brain tumours. We aimed to explore the
natural course of epileptic seizures, their predictors and the prognostic significance of their …

Objective: Because the d-2-hydroxyglutarate (D2HG) product of mutant isocitrate
dehydrogenase 1 (IDH1mut) is released by tumor cells into the microenvironment and is …

Primary intracranial tumors of the brain structures, including meninges, are rare with an
overall five-year survival rate of 33.4%; they are collectively called primary brain tumors …