Evidence suggests that gut microbiota composition and diversity can be a determinant of
skeletal muscle metabolism and functionality. This is true in catabolic (sarcopenia and …

The gut microbiota represents a 'metabolic organ'that can regulate human metabolism. Intact
gut microbiota contributes to host homeostasis, whereas compositional perturbations …

The progressive loss of skeletal muscle mass and concomitant reduction in contractile
strength plays a central role in frailty syndrome. Age-related neuronal impairments are …

Bone marrow mesenchymal stem cell (BMSC) osteogenic differentiation and osteoblast
function play critical roles in bone formation, which is a highly regulated process. Long …

Sarcopenia is a severe condition common to various chronic diseases and it is reckoned as
a major health problem. It encompasses many different molecular mechanisms that have …

Sarcopenia, characterized by loss of skeletal muscle mass, quality, and strength, has
become a common hallmark of ageing and many chronic diseases. Diabetes mellitus …

Aging promotes most degenerative pathologies in mammals, which are characterized by
progressive decline of function at molecular, cellular, tissue, and organismal levels and …

With the global increase of the elderly population, the improvement of the treatment for
various aging-related diseases and the extension of a healthy lifespan have become some …

Microplastics (MPs) have become increasingly serious global problems due to their wide
distribution and complicated impacts on living organisms. To obtain a comprehensive …

Ageing is a complex biological process associated with increased morbidity and mortality.
Nine classic, interdependent hallmarks of ageing have been proposed involving genetic and …