The transforming growth factor-β (TGF-β) is the prototype of the TGF-β family of growth and
differentiation factors, which is encoded by 33 genes in mammals and comprises homo-and …

Neurogenesis is an important process in the regulation of brain function and behaviour,
highly active in early development and continuing throughout life. Recent studies have …

Spatially resolved transcriptomics provides genetic information in space toward elucidation
of the spatial architecture in intact organs and the spatially resolved cell-cell …

Objectives Many studies have reported the increased presence of gastrointestinal (GI)
symptoms in children with autism spectrum disorders (ASD). Altered microbiome profiles …

Inflammation has been described for two millennia, but cellular aspects and the paradigm
involving different mediators have been identified in the recent century. Two main groups of …

Alzheimer9s disease (AD) is characterized by progressive cognitive decline, increasingly
attributed to neuronal dysfunction induced by amyloid-β oligomers (AβOs). Although the …

Assembly of synapses requires proper coordination between pre-and postsynaptic
elements. Identification of cellular and molecular events in synapse formation and …

We present a spatio-temporal assessment of microRNA (miRNA) expression throughout
early human brain development. We assessed the prefrontal cortex, hippocampus and …

The human genome encodes a vast repertoire of protein non-coding RNAs (ncRNA), some
specific to the brain. MicroRNAs, which interfere with the translation of target mRNAs, are of …

After accumulation of data showing that resident brain cells (neurons, astrocytes, and
microglia) produce mediators of the immune system, such as cytokines and their receptors …