Immune imprinting and next-generation coronavirus vaccines

CQ Huang, S Vishwanath, GW Carnell, ACY Chan… - Nature …, 2023 - nature.com
Vaccines based on historical virus isolates provide limited protection from continuously
evolving RNA viruses, such as influenza viruses or coronaviruses, which occasionally spill …

Heterologous prime–boost strategies for COVID-19 vaccines

B Sapkota, B Saud, R Shrestha… - Journal of travel …, 2022 - academic.oup.com
Abstract Background/Objective Heterologous prime–boost doses of COVID-19 vaccines
('mix-and-match'approach) are being studied to test for the effectiveness of Oxford …

[HTML][HTML] Long-term perturbation of the peripheral immune system months after SARS-CoV-2 infection

FJ Ryan, CM Hope, MG Masavuli, MA Lynn… - BMC medicine, 2022 - Springer
Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly
infectious respiratory virus which is responsible for the coronavirus disease 2019 (COVID …

[HTML][HTML] The COVID-19 pandemic in the African continent

G Bwire, AR Ario, P Eyu, F Ocom, JF Wamala, KA Kusi… - BMC medicine, 2022 - Springer
In December 2019, a new coronavirus, severe acute respiratory syndrome coronavirus-2
(SARS-CoV-2) and associated disease, coronavirus disease 2019 (COVID-19), was …

[HTML][HTML] SARS-CoV-2 humoral and cellular immunity following different combinations of vaccination and breakthrough infection

J Pušnik, WO Monzon-Posadas, J Zorn… - Nature …, 2023 - nature.com
The elicited anti-SARS-CoV-2 immunity is becoming increasingly complex with individuals
receiving a different number of vaccine doses paired with or without recovery from …

[HTML][HTML] Human coronaviruses: Origin, host and receptor

G Tang, Z Liu, D Chen - Journal of Clinical Virology, 2022 - Elsevier
Coronavirus is a type of RNA-positive single-stranded virus with an envelope, and the
spines on its surface derived its official name. Seven human coronaviruses 229E, OC43 …

The role of immune activation and antigen persistence in acute and long COVID

S Opsteen, JK Files, T Fram… - Journal of Investigative …, 2023 - journals.sagepub.com
In late 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) triggered the
global coronavirus disease 2019 (COVID-19) pandemic. Although most infections cause a …

A chitosan-mediated inhalable nanovaccine against SARS-CoV-2

SH Zhuo, JJ Wu, L Zhao, WH Li, YF Zhao, YM Li - Nano Research, 2022 - Springer
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), with several antigenic
variants, has grown into a global challenge, and the rapid establishment of an immune …

[HTML][HTML] Adaptive immunity to SARS-CoV-2 infection: A systematic review

MJA Silva, LR Ribeiro, KVB Lima… - Frontiers in …, 2022 - frontiersin.org
Background There is evidence that the adaptive or acquired immune system is one of the
crucial variables in differentiating the course of coronavirus disease 2019 (COVID-19) …

[HTML][HTML] Maintenance of broad neutralizing antibodies and memory B cells 1 year post-infection is predicted by SARS-CoV-2-specific CD4+ T cell responses

H Balachandran, C Phetsouphanh, D Agapiou… - Cell reports, 2022 - cell.com
Understanding the long-term maintenance of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) immunity is critical for predicting protection against reinfection …