Population balance modeling: current status and future prospects

D Ramkrishna, MR Singh - Annual review of chemical and …, 2014 - annualreviews.org
Population balance modeling is undergoing phenomenal growth in its applications, and this
growth is accompanied by multifarious reviews. This review aims to fortify the model's …

Application of flow cytometry to industrial microbial bioprocesses

M Díaz, M Herrero, LA García, C Quirós - Biochemical engineering journal, 2010 - Elsevier
Flow cytometry (FC) is a powerful technique for the rapid analysis of single cells in a mixture,
by means of light-scattering and fluorescence measurements. In biotechnology, the power of …

Experimental methods and modeling techniques for description of cell population heterogeneity

RL Fernandes, M Nierychlo, L Lundin… - Biotechnology …, 2011 - Elsevier
With the continuous development, in the last decades, of analytical techniques providing
complex information at single cell level, the study of cell heterogeneity has been the focus of …

Optimization of yeast cell cycle analysis and morphological characterization by multispectral imaging flow cytometry

MEK Calvert, JA Lannigan… - Cytometry Part A: The …, 2008 - Wiley Online Library
Budding yeast Saccharoymyces cerevisiae is a powerful model system for analyzing
eukaryotic cell cycle regulation. Yeast cell cycle analysis is typically performed by visual …

Digital image analysis of yeast single cells growing in two different oxygen concentrations to analyze the population growth and to assist individual-based modeling

M Ginovart, R Carbó, M Blanco, X Portell - Frontiers in Microbiology, 2018 - frontiersin.org
Nowadays control of the growth of Saccharomyces to obtain biomass or cellular wall
components is crucial for specific industrial applications. The general aim of this contribution …

A novel mathematical model to simulate the size-structured growth of microalgae strains dividing by multiple fission

A Concas, M Pisu, G Cao - Chemical Engineering Journal, 2016 - Elsevier
Several microalgae strains are capable to divide by multiple fission, namely they can give
rise to variable number of daughter cells after cytokinesis. Such behavior may have …

Conservative finite volume method on deforming geometries: The case of protein aggregation in dividing yeast cells

AA Heydari, SS Sindi, M Theillard - Journal of Computational Physics, 2022 - Elsevier
Motivated by experimental observations of asymmetric protein aggregates distributions in
dividing yeast cells, we present a conservative finite volume approach for reaction-diffusion …

Prion dynamics and the quest for the genetic determinant in protein-only inheritance

SS Sindi, TR Serio - Current opinion in microbiology, 2009 - Elsevier
According to the prion hypothesis, proteins may act in atypical roles as genetic elements of
infectivity and inheritance by undergoing self-replicating changes in physical state. While the …

Cell mass and cell cycle dynamics of an asynchronous budding yeast population: experimental observations, flow cytometry data analysis, and multi‐scale modeling

RL Fernandes, M Carlquist, L Lundin… - Biotechnology and …, 2013 - Wiley Online Library
Despite traditionally regarded as identical, cells in a microbial cultivation present a
distribution of phenotypic traits, forming a heterogeneous cell population. Moreover, the …

Exploring the lag phase and growth initiation of a yeast culture by means of an individual-based model

M Ginovart, C Prats, X Portell, M Silbert - Food microbiology, 2011 - Elsevier
The performance of fermentation processes is greatly influenced by the size and quality of
inocula. The characterization of the replicative age is decided by the number of birth scars …