Implementation of protocolized surveillance, diagnosis, and management of septic patients,
and of surgical sepsis patients in particular, is shown to result in significantly increased …

Sepsis and trauma were the primary inciting events. With tremendous the advances in care
over the ensuing four decades, the epidemiology of MOF evolved from a fulminant …

The premier single-volume reference in the field of anesthesia, Clinical Anesthesia is now in
its Sixth Edition, with thoroughly updated coverage, a new full-color design, and a revamped …

Recent studies have identified that N6-methyladenosine (m6A) extensively participates in
the myocardial injury pathophysiological process. However, the role of m6A on sepsis …

Sepsis is characterised by a dysregulated host immune response to infection. Despite
recognition of its significance, immune status monitoring is not implemented in clinical …

Objective: To analyze serial biomarkers of the persistent inflammation, immunosuppression,
and catabolism syndrome (PICS) to gain insight into the pathobiology of chronic critical …

Background With the successful implementation of the Surviving Sepsis Campaign
guidelines, post-sepsis in-hospital mortality to sepsis continues to decrease. Those who …

Sepsis, a heterogeneous clinical syndrome, features a systemic inflammatory response to
tissue injury or infection, followed by a state of reduced immune responsiveness …

BACKGROUND Sepsis remains a major clinical challenge for which successful treatment
requires greater precision in identifying patients at increased risk of adverse outcomes …

It is evident that the admission of some patients with sepsis and septic shock to hospitals is
occurring late in their illness, which has contributed to the increase in poor outcomes and …