[HTML][HTML] Physiologically based pharmacokinetic modeling of nanoparticle biodistribution: a review of existing models, simulation software, and data analysis tools

EO Kutumova, IR Akberdin, IN Kiselev… - International Journal of …, 2022 - mdpi.com
Cancer treatment and pharmaceutical development require targeted treatment and less toxic
therapeutic intervention to achieve real progress against this disease. In this scenario …

Local Identifiability Analysis, Parameter Subset Selection and Verification for a Minimal Brain PBPK Model

K Dadashova, RC Smith, MA Haider - Bulletin of Mathematical Biology, 2024 - Springer
Physiologically-based pharmacokinetic (PBPK) modeling is important for studying drug
delivery in the central nervous system, including determining antibody exposure, predicting …