[HTML][HTML] The role of IL-6 in fibrotic diseases: molecular and cellular mechanisms

Y Li, J Zhao, Y Yin, K Li, C Zhang… - International journal of …, 2022 - ncbi.nlm.nih.gov
Fibrosis is a detrimental outcome of most chronic inflammatory disorders and is defined by
the buildup of excess extracellular matrix (ECM) components, which eventually leads to …

Astragalus and its formulas as a therapeutic option for fibrotic diseases: Pharmacology and mechanisms

Y Zhu, Y Chai, G Xiao, Y Liu, X Xie, W Xiao… - Frontiers in …, 2022 - frontiersin.org
Fibrosis is the abnormal deposition of extracellular matrix, characterized by accumulation of
collagen and other extracellular matrix components, which causes organ dysfunction and …

Fibrosis of peritoneal membrane as target of new therapies in peritoneal dialysis

V Masola, M Bonomini, S Borrelli, L Di Liberato… - International journal of …, 2022 - mdpi.com
Peritoneal dialysis (PD) is an efficient renal replacement therapy for patients with end-stage
renal disease. Even if it ensures an outcome equivalent to hemodialysis and a better quality …

SGLT2 inhibition by intraperitoneal dapagliflozin mitigates peritoneal fibrosis and ultrafiltration failure in a mouse model of chronic peritoneal exposure to high-glucose …

MS Balzer, S Rong, J Nordlohne, JD Zemtsovski… - Biomolecules, 2020 - mdpi.com
Peritoneal dialysis (PD) is limited by glucose-mediated peritoneal membrane (PM) fibrosis,
angiogenesis, and ultrafiltration failure. Influencing PM integrity by pharmacologically …

[HTML][HTML] Gasotransmitters: Potential therapeutic molecules of fibrotic diseases

Y Chen, S Yuan, Y Cao, G Kong, F Jiang, Y Li… - … Medicine and Cellular …, 2021 - hindawi.com
Fibrosis is defined as the pathological progress of excessive extracellular matrix (ECM),
such as collagen, fibronectin, and elastin deposition, as the regenerative capacity of cells …

How to improve the biocompatibility of peritoneal dialysis solutions (without jeopardizing the patient's health)

M Bonomini, V Masola, G Procino, V Zammit… - International Journal of …, 2021 - mdpi.com
Peritoneal dialysis (PD) is an important, if underprescribed, modality for the treatment of
patients with end-stage kidney disease. Among the barriers to its wider use are the …

Advances in stem cell therapy for peritoneal fibrosis: from mechanisms to therapeutics

W Huang, D Xia, W Bi, X Lai, B Yu, W Chen - Stem Cell Research & …, 2023 - Springer
Peritoneal fibrosis (PF) is a pathophysiological condition caused by a variety of pathogenic
factors. The most important features of PF are mesothelial–mesenchymal transition and …

A new peritoneal dialysis solution containing L-carnitine and xylitol for patients on continuous ambulatory peritoneal dialysis: First clinical experience

C Rago, T Lombardi, G Di Fulvio, L Di Liberato… - Toxins, 2021 - mdpi.com
Peritoneal dialysis (PD) is a feasible and effective renal replacement therapy (RRT) thanks
to the dialytic properties of the peritoneal membrane (PM). Preservation of PM integrity and …

Autophagy in peritoneal fibrosis

H Su, J Yang, R Zou, N An, X Chen, C Yang… - Frontiers in …, 2023 - frontiersin.org
Peritoneal dialysis (PD) is a widely accepted renal replacement therapy for patients with end-
stage renal disease (ESRD). Morphological and functional changes occur in the peritoneal …

[HTML][HTML] Pharmacologic inhibition of histone deacetylase 6 prevents the progression of chlorhexidine gluconate-induced peritoneal fibrosis by blockade of M2 …

Y Shi, J Li, H Chen, Y Hu, L Tang, X Zhou… - Frontiers in …, 2022 - frontiersin.org
Peritoneal fibrosis contributes to ultrafiltration failure in peritoneal dialysis (PD) patients and
thus restricts the wide application of PD in clinic. Recently we have demonstrated that …