The Bacillus cereus group includes several Bacillus species with closely related phylogeny.
The most well-studied members of the group, B. anthracis, B. cereus, and B. thuringiensis …

Bacterial sepsis is a major cause of fatality worldwide. Sepsis is a multi-step process that
involves an uncontrolled inflammatory response by the host cells that may result in multi …

Anthrax is caused by the spore-forming, gram-positive bacterium Bacillus anthracis. The
bacterium's major virulence factors are (a) the anthrax toxins and (b) an antiphagocytic …

The pathophysiological effects resulting from many bacterial diseases are caused by
exotoxins released by the bacteria. Bacillus anthracis, a spore-forming bacterium, is such a …

Bacterial toxins are virulence factors that manipulate host cell functions and take over the
control of vital processes of living organisms to favor microbial infection. Some toxins directly …

Bacillus anthracis infects hosts as a spore, germinates, and disseminates in its vegetative
form. Production of anthrax lethal and edema toxins following bacterial outgrowth results in …

Many bacterial and viral pathogens block or subvert host cellular processes to promote
successful infection. One host protein that is targeted by invading pathogens is the small …

Morbidity and mortality from sepsis remains unacceptably high. Large variability in clinical
practice, plus the increasing awareness that certain processes of care associated with …

Anthrax is an infectious disease of relevance for military forces. Although spores of Bacillus
anthracis obiquitously occur in soil, reports on soil-borne transmission to humans are …

Anthrax lethal toxin (LT), a major virulence determinant of anthrax disease, induces vascular
collapse in mice and rats. LT activates the Nlrp1 inflammasome in macrophages and …