[PDF][PDF] Gut microbiota-derived bile acids in intestinal immunity, inflammation, and tumorigenesis

J Cai, L Sun, FJ Gonzalez - Cell host & microbe, 2022 - cell.com
Inflammatory bowel disease (IBD) and colorectal cancer (CRC) are heterogeneous intestinal
diseases that threaten the health of an increasing number of individuals as their lifestyles …

Targeting IL-6 trans-signalling: past, present and future prospects

S Rose-John, BJ Jenkins, C Garbers, JM Moll… - Nature Reviews …, 2023 - nature.com
Abstract Interleukin-6 (IL-6) is a key immunomodulatory cytokine that affects the
pathogenesis of diverse diseases, including autoimmune diseases, chronic inflammatory …

[PDF][PDF] Targeted suppression of human IBD-associated gut microbiota commensals by phage consortia for treatment of intestinal inflammation

S Federici, S Kredo-Russo, R Valdés-Mas… - Cell, 2022 - cell.com
Human gut commensals are increasingly suggested to impact non-communicable diseases,
such as inflammatory bowel diseases (IBD), yet their targeted suppression remains a …

Analysis of microplastics in human feces reveals a correlation between fecal microplastics and inflammatory bowel disease status

Z Yan, Y Liu, T Zhang, F Zhang, H Ren… - … science & technology, 2021 - ACS Publications
Human ingestion of microplastics (MPs) is inevitable due to the ubiquity of MPs in various
foods and drinking water. Whether the ingestion of MPs poses a substantial risk to human …

Global, regional and national burden of inflammatory bowel disease in 204 countries and territories from 1990 to 2019: a systematic analysis based on the Global …

R Wang, Z Li, S Liu, D Zhang - BMJ open, 2023 - bmjopen.bmj.com
Objectives We aimed to provide the most updated estimates on the global burden of
inflammatory bowel disease (IBD) to improve management strategies. Design We extracted …

The four epidemiological stages in the global evolution of inflammatory bowel disease

GG Kaplan, JW Windsor - Nature reviews Gastroenterology & …, 2021 - nature.com
Inflammatory bowel disease (IBD) is a global disease; its evolution can be stratified into four
epidemiological stages: Emergence, Acceleration in Incidence, Compounding Prevalence …

Interaction between microbiota and immunity in health and disease

D Zheng, T Liwinski, E Elinav - Cell research, 2020 - nature.com
The interplay between the commensal microbiota and the mammalian immune system
development and function includes multifold interactions in homeostasis and disease. The …

Crohn's disease

G Roda, S Chien Ng, PG Kotze, M Argollo… - Nature Reviews …, 2020 - nature.com
Crohn's disease is an inflammatory bowel disease that is characterized by chronic
inflammation of any part of the gastrointestinal tract, has a progressive and destructive …

Microbiome risk profiles as biomarkers for inflammatory and metabolic disorders

A Metwaly, S Reitmeier, D Haller - Nature reviews Gastroenterology & …, 2022 - nature.com
The intestine harbours a complex array of microorganisms collectively known as the gut
microbiota. The past two decades have witnessed increasing interest in studying the gut …

Immune regulation by fungal strain diversity in inflammatory bowel disease

XV Li, I Leonardi, GG Putzel, A Semon, WD Fiers… - Nature, 2022 - nature.com
The fungal microbiota (mycobiota) is an integral part of the complex multikingdom microbial
community colonizing the mammalian gastrointestinal tract and has an important role in …