The immune system is generally known to be the primary defense mechanism against
pathogens. Any pathological conditions are reflected in anomalies in the immune system …

Schizophrenia has been an evolutionary paradox: it has high heritability, but it is associated
with decreased reproductive success. The causal genetic variants underlying schizophrenia …

Microbiome data predictive analysis within a machine learning (ML) workflow presents
numerous domain-specific challenges involving preprocessing, feature selection, predictive …

BackgroundAccumulating evidence suggests that positive and negative emotions, as well as
emotion regulation, play key roles in human health and disease. Recent work has shown the …

The microbiota-gut-brain axis is a complex interconnected system altered in schizophrenia.
The antioxidant N-acetylcysteine (NAC) has been proposed as an adjunctive therapy to …

The prevalence of schizophrenia, affecting approximately 1% of the global population,
underscores the urgency for innovative therapeutic strategies. Recent insights into the role …

Background Altered intestinal permeability and low-grade chronic inflammation disrupt the
integrity of the blood–brain barrier (microbiota–gut–brain axis), probably playing a role in the …

Balanced fear supports human rational decision-making and useful behavioral responses.
In contrast, overwhelming, persistent, and unbalanced fear can paralyze the individual and …

The influence of gut microbiota in the onset and development of several metabolic diseases
has gained attention over the last few years. Diet plays an essential role in gut microbiota …

Background Schizophrenia (SCZ) is a heritable disorder with a polygenic architecture, and
the gut microbiota seems to be involved in its development and outcome. In this study, we …