Biological and technical challenges for implementation of yeast‐based biosensors

E Wahid, OB Ocheja, E Marsili… - Microbial …, 2023 - Wiley Online Library
Biosensors are low‐cost and low‐maintenance alternatives to conventional analytical
techniques for biomedical, industrial and environmental applications. Biosensors based on …

Synthetic biology for microbial heavy metal biosensors

HJ Kim, H Jeong, SJ Lee - Analytical and bioanalytical chemistry, 2018 - Springer
Using recombinant DNA technology, various whole-cell biosensors have been developed
for detection of environmental pollutants, including heavy metal ions. Whole-cell biosensors …

Orthogonal paper biosensor for mercury (II) combining bioluminescence and colorimetric smartphone detection

A Lopreside, L Montali, B Wang, A Tassoni… - Biosensors and …, 2021 - Elsevier
Mercury contamination in the environment has reached alarming levels. Due to its
persistence and bioaccumulation, mercury is one of the most widespread toxic heavy metals …

Heavy metal whole-cell biosensors using eukaryotic microorganisms: an updated critical review

JC Gutiérrez, F Amaro, A Martín-González - Frontiers in microbiology, 2015 - frontiersin.org
This review analyzes the advantages and disadvantages of using eukaryotic
microorganisms to design whole-cell biosensors (WCBs) for monitoring environmental …

Smartphone-interfaced 3D printed toxicity biosensor integrating bioluminescent “sentinel cells”

L Cevenini, MM Calabretta, G Tarantino… - Sensors and Actuators B …, 2016 - Elsevier
In this work, we report the design, fabrication, and preliminary assessment of analytical
performance of a smartphone-based bioluminescence (BL) whole-cell toxicity biosensor …

Synthetic biology tools for environmental protection

J Aminian-Dehkordi, S Rahimi, M Golzar-Ahmadi… - Biotechnology …, 2023 - Elsevier
Synthetic biology transforms the way we perceive biological systems. Emerging
technologies in this field affect many disciplines of science and engineering. Traditionally …

Yeast biosensors for detection of environmental pollutants: current state and limitations

S Jarque, M Bittner, L Blaha, K Hilscherova - Trends in biotechnology, 2016 - cell.com
Yeast biosensors have become suitable tools for the screening and detection of
environmental pollutants because of their various advantages compared to other sensing …

Engineering Saccharomyces cerevisiae‐based biosensors for copper detection

C Fan, D Zhang, Q Mo, J Yuan - Microbial Biotechnology, 2022 - Wiley Online Library
Heavy metals, that is Cu (II), are harmful to the environment. There is an increasing demand
to develop inexpensive detection methods for heavy metals. Here, we developed a yeast …

A luciferase mutant with improved brightness and stability for whole-cell bioluminescent biosensors and in vitro biosensing

MM Calabretta, D Gregucci, H Martínez-Pérez-Cejuela… - Biosensors, 2022 - mdpi.com
The availability of new bioluminescent proteins with tuned properties, both in terms of
emission wavelength, kinetics and protein stability, is highly valuable in the bioanalytical …

Yeast-based biosensors: current applications and new developments

H Martin-Yken - Biosensors, 2020 - mdpi.com
Biosensors are regarded as a powerful tool to detect and monitor environmental
contaminants, toxins, and, more generally, organic or chemical markers of potential threats …