Chronic Kidney Disease (CKD) is a global health burden with high mortality and health
costs. CKD patients exhibit lower cardiorespiratory and muscular fitness, strongly associated …

Reactive oxygen and nitrogen species (ROS and RNS, respectively) are part of any aerobic
lifestyle/metabolism: low (ie, subtoxic) concentrations of selected ROS and RNS are …

Bombyx mori was used to study the molecular mechanism of fluoride induced reproductive
toxicity. In our previous study, we confirmed the physiological and biochemical effects of NaF …

Cigarette smoke is a well-established exogenous risk factor containing toxic reactive
molecules able to induce oxidative stress, which in turn contributes to smoking-related …

Background Oxidative stress, a commonly used paradigm to explain nanoparticle (NP)-
induced toxicity, results from an imbalance between reactive oxygen species (ROS) …

DJ-1 is a causative gene for familial Parkinson's disease (PD) with different functions,
standing out its role against oxidative stress (OS). Accordingly, PD model flies harboring a …

Background The cytoskeleton, unlike the bony vertebrate skeleton or the exoskeleton of
invertebrates, is a highly dynamic meshwork of protein filaments that spans through the …

Smoking increases the risk of cardiovascular disorders and leads to damage caused by
inflammation and oxidative stress. The actin cytoskeleton is a key player in the response to …

Patients with peripheral artery disease (PAD) have increased mortality rates and a myopathy
in their affected legs which is characterized by increased oxidative damage, reduced …

Ageing is a complex deteriorating process that coincides with changes in metabolism,
replicative senescence, increased resistance to apoptosis, as well as progressive …