[HTML][HTML] Unusual CD4+ CD28− T cells and their pathogenic role in chronic inflammatory disorders
GH Lee, WW Lee - Immune network, 2016 - ncbi.nlm.nih.gov
CD28 is a primary co-stimulatory receptor that is essential for successful T cell activation,
proliferation, and survival. While ubiquitously expressed on naive T cells, the level of CD28 …
proliferation, and survival. While ubiquitously expressed on naive T cells, the level of CD28 …
[HTML][HTML] Immunosenescence and multiple sclerosis: inflammaging for prognosis and therapeutic consideration
S Thakolwiboon, EA Mills, J Yang, J Doty… - Frontiers in …, 2023 - ncbi.nlm.nih.gov
Aging is associated with a progressive decline of innate and adaptive immune responses,
called immunosenescence. This phenomenon links to different multiple sclerosis (MS) …
called immunosenescence. This phenomenon links to different multiple sclerosis (MS) …
The effect of age on the immunogenicity of the live attenuated zoster vaccine is predicted by baseline regulatory T cells and varicella-zoster virus-specific T cell …
A Weinberg, L Pang, MJ Johnson, Y Caldas… - Journal of …, 2019 - Am Soc Microbiol
Older age is associated with increased infectious morbidity and decreased immune
responses to vaccines, but the mechanisms that mediate this effect are incompletely …
responses to vaccines, but the mechanisms that mediate this effect are incompletely …
Perceived stress, cytomegalovirus titers, and late-differentiated T and NK cells: Between-, within-person associations in a longitudinal study of older adults
RG Reed, SR Presnell, A Al-Attar, CT Lutz… - Brain, behavior, and …, 2019 - Elsevier
Cytomegalovirus (CMV) and psychological stress are implicated as drivers of immunological
aging. It is unknown, however, whether associations among CMV titers, stress, and immune …
aging. It is unknown, however, whether associations among CMV titers, stress, and immune …
Terminally differentiated effector memory T cells associate with cognitive and AD-related biomarkers in an aging-based community cohort
E Winford, J Lutshumba, BJ Martin, DM Wilcock… - Immunity & …, 2024 - Springer
Background and purpose The immune response changes during aging and the progression
of Alzheimer's disease (AD) and related dementia (ADRD). Terminally differentiated effector …
of Alzheimer's disease (AD) and related dementia (ADRD). Terminally differentiated effector …
Income and markers of immunological cellular aging
Objective Socioeconomic disadvantage may contribute to poor health through immune-
related biological mechanisms. We examined the associations between socioeconomic …
related biological mechanisms. We examined the associations between socioeconomic …
Predisposing factors in acute-on-chronic liver failure
J Trebicka - Seminars in liver disease, 2016 - thieme-connect.com
Acute-on-chronic liver failure (ACLF) is a syndrome with high short-term mortality in patients
with chronic liver disease. The definition of ACLF has been addressed recently in many …
with chronic liver disease. The definition of ACLF has been addressed recently in many …
Peripheral blood T-cell signatures from high-resolution immune phenotyping of γδ and αβ T-cells in younger and older subjects in the Berlin Aging Study II
K Wistuba-Hamprecht, K Haehnel, N Janssen… - Immunity & …, 2015 - Springer
Background Aging and latent infection with Cytomegalovirus (CMV) are thought to be major
factors driving the immune system towards immunosenescence, primarily characterized by …
factors driving the immune system towards immunosenescence, primarily characterized by …
Latent CMV infection is associated with lower influenza virus-specific memory T-cell frequencies, but not with an impaired T-cell response to acute influenza virus …
SPH Van den Berg, J Lanfermeijer… - Frontiers in …, 2021 - frontiersin.org
Latent infection with cytomegalovirus (CMV) is assumed to contribute to the age-associated
decline of the immune system. CMV induces large changes in the T-cell pool and may …
decline of the immune system. CMV induces large changes in the T-cell pool and may …
Age-related adaptive immune changes in Parkinson's disease
A Kouli, CH Williams-Gray - Journal of Parkinson's Disease, 2022 - content.iospress.com
Ageing is a major risk factor for most neurodegenerative diseases, including Parkinson's
disease (PD). Progressive age-related dysregulation of the immune system is termed …
disease (PD). Progressive age-related dysregulation of the immune system is termed …