Healthy aging is partly related to appropriate function of the immune system. As already
reported, some changes in this system are observed, including reduced number and …

A latent infection with cytomegalovirus (CMV), a ubiquitous beta herpesvirus, is associated
with an accumulation of late-differentiated memory T-cells, often accompanied by a …

Purpose There are well-known alterations occurring within the immune system with aging.
Collectively, these changes are known as immunosenescence. The incidence of …

Human cytomegalovirus (HCMV) is a ubiquitous β-herpes virus that has co-evolved with its
host since the very beginning of human life. The vast majority of adults worldwide carry the …

Abstract “Immunosenescence” has been invoked as the root cause of increased incidence
and severity of infectious disease in older adults and their poorer response to vaccination …

Dynamic exercise evokes a rapid redeployment of cytotoxic T cell subsets with high
expression of β 2 adrenergic receptors, presumably to enhance immunosurveillance during …

The mechanisms regulating memory CD8+ T cell function and homeostasis during aging are
unclear. CD8+ effector memory T cells that re-express CD45RA increase considerably in …

Background Cytomegalovirus (CMV) infection has been reported to contribute to the
pathogenesis of type 1 diabetes and post-transplantation diabetes. However, CMV infection …

A number of biological parameters have been cited as hallmarks of immune aging.
However, it is not clear whether these multiple biological changes are the result of common …

The elderly population is more susceptible to infections as a result of an altered immune
response, commonly referred to as immunosenescence. Cytomegalovirus (CMV)-infection …