The precorneal tear film is a complex mixture of proteins, lipids, metabolites, and electrolytes
with different structures and functionalities. Sustainable production of each tear component …

Purpose.: A prospective, multisite clinical study (10 sites in the European Union and the
United States) evaluated the clinical utility of commonly used tests and tear osmolarity for …

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Dry eye is a common ocular surface inflammatory disease that significantly affects quality of
life. Dysfunction of the lacrimal function unit (LFU) alters tear composition and breaks ocular …

Background Theoretically, autologous serum eye drops (AS) offer a potential advantage
over traditional therapies on the assumption that AS not only serve as a lacrimal substitute to …

Publication of the DEWS report in 2007 established the state of the science of dry eye
disease (DED). Since that time, new evidence suggests that a rethinking of traditional …

Purpose To provide a consensus clinical guideline for management of dry eye disease
associated with Sjögren disease by evaluating published treatments and recommending …

Purpose To evaluate the effects of tear osmolarity on the repeatability of keratometry (K)
measurements in patients presenting for cataract surgery. Setting Three clinical practices …

Purpose Inflammatory molecules have been demonstrated in the tear film of patients with
severe dry eye disease (DED). However, little attention has been paid to the most frequent …

Dry eye disease (DED) is a distressing ocular condition. Due to its multifactorial nature,
clinical and biological signs of DED can be inconsistent and sometimes discordant with …