This review discusses the current understanding of tear-film physiology and mathematical
models for some of its dynamics. First, a brief introduction to the tear film and the ocular …

The tear film is a nourishing, lubricating and protecting layer that bathes the ocular surface. It
is continuously replenished through cycles of production and elimination via evaporation …

Great strides have recently been made in quantitative measurements of tear film thickness
and thinning, mathematical modeling thereof and linking these to sensory perception. This …

Purpose: Tear film hyperosmolarity is recognized as an important pathogenetic factor in dry
eye syndrome, but difficulties in its measurement have limited its utility in the recent past …

Dry eye is an inflammatory disease that results from activation of innate inflammatory
pathways in resident ocular surface cells, as well as cytokines produced by recruited T …

Aims This study was performed to investigate the correlation between dry eye disease and
diabetes microvascular complications. Methods In this study 243 people with type 2 diabetes …

purpose. To determine the most effective objective tests, applied singly or in combination in
the diagnosis of dry eye disease. methods. Two groups of subjects—41 with dry eye and 32 …

PURPOSE: To evaluate the efficacy of three commercially available lubricant eye drops for
the treatment of mild, dry, irritated eyes. METHODS: Randomized, investigator-masked …

purpose. To measure the upper and lower tear menisci in patients with aqueous tear
deficiency (ATD) dry eye by real-time optical coherence tomography (OCT) and to determine …

Purpose.: To study the association between tear osmolarity and dry eye severity grade,
based on a modified Dry Eye Workshop (DEWS) scale, and between osmolarity and the …