[HTML][HTML] The SARS-CoV-2 mutations versus vaccine effectiveness: New opportunities to new challenges

JA Malik, S Ahmed, A Mir, M Shinde, O Bender… - Journal of infection and …, 2022 - Elsevier
Abstract Background The SARS-CoV-2 coronavirus epidemic is hastening the discovery of
the most efficient vaccines. The development of cost-effective vaccines seems to be the only …

[HTML][HTML] SARS-CoV-2 vaccines based on the spike glycoprotein and implications of new viral variants

D Martínez-Flores, J Zepeda-Cervantes… - Frontiers in …, 2021 - frontiersin.org
Coronavirus 19 Disease (COVID-19) originating in the province of Wuhan, China in 2019, is
caused by the severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2), whose …

Intranasal vaccines for SARS-CoV-2: From challenges to potential in COVID-19 management

VP Chavda, LK Vora, AK Pandya, VB Patravale - Drug discovery today, 2021 - Elsevier
Abstract Unlike conventional Coronavirus 2019 (COVID-19) vaccines, intranasal vaccines
display a superior advantage because the nasal mucosa is often the initial site of infection …

[HTML][HTML] WHO International Standard for evaluation of the antibody response to COVID-19 vaccines: call for urgent action by the scientific community

I Knezevic, G Mattiuzzo, M Page, P Minor… - The Lancet …, 2022 - thelancet.com
Summary The first WHO International Standard and International Reference Panel for anti-
SARS-CoV-2 immunoglobulin were established by the WHO Expert Committee on …

[HTML][HTML] The impact of spike mutated variants of SARS-CoV2 [Alpha, Beta, Gamma, Delta, and Lambda] on the efficacy of subunit recombinant vaccines

M Mohammadi, M Shayestehpour… - Brazilian Journal of …, 2021 - SciELO Brasil
Since the first described human infection with SARS-CoV-2 in December of 2019 many
subunit protein vaccines have been proposed for use in humans. Subunit vaccines use one …

Mechanisms of SARS-CoV-2 evolution revealing vaccine-resistant mutations in Europe and America

R Wang, J Chen, GW Wei - The journal of physical chemistry …, 2021 - ACS Publications
The importance of understanding SARS-CoV-2 evolution cannot be overlooked. Recent
studies confirm that natural selection is the dominating mechanism of SARS-CoV-2 …

[HTML][HTML] Nucleic acid vaccines for COVID-19: a paradigm shift in the vaccine development arena

VP Chavda, MK Hossain, J Beladiya, V Apostolopoulos - Biologics, 2021 - mdpi.com
Coronavirus disease, COVID-19, has touched every country globally except five countries
(North Korea, Turkmenistan, Tonga, Tuvalu and Nauru). Vaccination is the most effective …

Recent advances and challenges in gene delivery mediated by polyester-based nanoparticles

A Piperno, MT Sciortino, E Giusto… - International Journal …, 2021 - Taylor & Francis
Gene therapy is a promising approach for the treatment of several diseases, such as chronic
or viral infections, inherited disorders, and cancer. The cellular internalization of exogenous …

Influence of age, gender, previous SARS-CoV-2 infection, and pre-existing diseases in antibody response after COVID-19 vaccination: A review

MCR Fernandes, GS Vasconcelos, ACL de Melo… - Molecular …, 2023 - Elsevier
Vaccines induce specific long-term immunological memory against pathogens, preventing
the worsening of diseases. The COVID-19 health emergency has caused more than 6 …

[HTML][HTML] The impact of COVID-19 on comorbidities: a review of recent updates for combating it

JA Malik, S Ahmed, M Shinde, MHS Almermesh… - Saudi journal of …, 2022 - Elsevier
Coronavirus disease is caused by the SARS-CoV-2 virus. The virus first appeared in Wuhan
(China) in December 2019 and has spread globally. Till now, it affected 269 million people …