Current treatment of Parkinson's disease (PD) ameliorates symptoms but fails to block
disease progression. This study was conducted to explore the protective effects of SVHRSP …

There is a well-established link between physical activity and brain health. As such, the
effectiveness of physical exercise as a therapeutic strategy has been explored in a variety of …

We present the first demonstration of chronic in vivo imaging of microglia in mice undergoing
voluntary wheel running. We find that healthy mice undergoing voluntary wheel running …

It has been widely documented that medicinal herbal remedies are effective, have fewer
side effects than conventional medicine, and have a synergistic effect on health …

Traumatic brain injury (TBI) is associated with an increased risk of developing Parkinson's
disease (PD), though the exact mechanisms remain unclear. TBI triggers acute …

Background Exercise plays an essential role in improving motor symptoms in Parkinson's
disease (PD), but the underlying mechanism in the central nervous system remains unclear …

Substantia nigra pars compacta (SNc) dopamine neurons are required for voluntary
movement and reward learning, and advanced age is associated with motor and cognitive …

Substantia nigra pars compacta (SNc) dopamine neurons are required for voluntary
movement and reward learning, and advanced age is associated with motor and cognitive …

Studies have demonstrated the role of neuroinflammation in Parkinson's disease (PD) and
other neurodegenerative diseases, which have an important role of microglial cells among …

We demonstrate the first use of chronic in vivo imaging of microglia over time during 23
physical exercise. We found that microglia movement, morphology, and process motility …