Renovascular hypertension

SM Herrmann, SC Textor - Endocrinology and Metabolism …, 2019 - endo.theclinics.com
Renovascular disease (RVD) is caused by progressive occlusive renal artery disease
presenting with a myriad of symptoms ranging from renovascular hypertension to ischemic …

Mitochondria: a pathogenic paradigm in hypertensive renal disease

A Eirin, A Lerman, LO Lerman - Hypertension, 2015 - Am Heart Assoc
Eirin et al Mitochondria in Hypertension 265 dysmotility. 20 Hypertrophic cardiomyopathy in
Leigh's syndrome results from mutations in the mitochondrial ATPase-6 gene. 21 Likewise …

Mesenchymal stem cell-derived extracellular vesicles improve the renal microvasculature in metabolic renovascular disease in swine

A Eirin, XY Zhu, S Jonnada, A Lerman… - Cell …, 2018 - journals.sagepub.com
Background: Extracellular vesicles (EVs) released from mesenchymal stem/stromal cells
(MSCs) mediate their paracrine effect, but their efficacy to protect the microcirculation of the …

Mitochondrial protection restores renal function in swine atherosclerotic renovascular disease

A Eirin, B Ebrahimi, X Zhang, XY Zhu… - Cardiovascular …, 2014 - academic.oup.com
Aims The mechanisms responsible for renal injury in atherosclerotic renovascular disease
(ARVD) are incompletely understood, and few therapeutic options are available to reverse it …

Kidney intrinsic mechanisms as novel targets in renovascular hypertension

A Eirin, AR Chade, LO Lerman - Hypertension, 2024 - Am Heart Assoc
Almost a hundred years have passed since obstruction of the renal artery has been
recognized to raise blood pressure. By now chronic renovascular disease (RVD) due to …

Renal ischemia induces epigenetic changes in apoptotic, proteolytic, and mitochondrial genes in swine scattered tubular-like cells

KS Rajagopalan, LM Glasstetter, XY Zhu, R Thaler… - Cells, 2022 - mdpi.com
Background: Scattered tubular-like cells (STCs) are dedifferentiated renal tubular cells
endowed with progenitor-like characteristics to repair injured parenchymal cells. STCs may …

Renal artery stenosis

JD Tafur-Soto, CJ White - Cardiology clinics, 2015 - cardiology.theclinics.com
Renal artery stenosis (RAS), the single largest cause of secondary hypertension affecting
25% to 35% of the patients with secondary hypertension, 1, 2 is associated with progressive …

Mesenchymal stem/stromal cell-derived extracellular vesicles elicit better preservation of the intra-renal microvasculature than renal revascularization in pigs with …

CM Ferguson, RA Farahani, XY Zhu, H Tang… - Cells, 2021 - mdpi.com
Background: Percutaneous transluminal renal angioplasty (PTRA) confers clinical and
mortality benefits in select 'high-risk'patients with renovascular disease (RVD). Intra-renal …

Atherosclerotic renal artery stenosis: current status

SH Kwon, LO Lerman - Advances in chronic kidney disease, 2015 - Elsevier
Atherosclerotic renal artery stenosis (ARAS) remains a major cause of secondary
hypertension and kidney failure. Randomized prospective trials show that medical treatment …

Inhibition mechanism of cordycepin and ergosterol from Cordyceps militaris Link. against xanthine oxidase and cyclooxygenase-2

HB Zhou, LJ Feng, XH Weng, T Wang, H Lu… - International Journal of …, 2024 - Elsevier
Cordyceps militaris Link.(C. militaris) is an entomopathogenic fungus that parasitizes the
pupa or cocoon of lepidopteran insect larvae, with various bioactive compounds …