Synergy of “Yiqi” and “Huoxue” components of QishenYiqi formula in ischemic stroke protection via lysosomal/inflammatory mechanisms

Y Wang, X Liu, W Zhang, S He, Y Zhang… - Journal of …, 2022 - Elsevier
Ethnopharmacological relevance Ischemic stroke is one of the leading causes of mortality
and long-term disability worldwide. Currently, approved therapies of intravenous …

A network pharmacology‐based approach to explore the effects of Chaihu Shugan powder on a non‐alcoholic fatty liver rat model through nuclear receptors

H Nie, Y Deng, C Zheng, M Pan, J Xie… - Journal of Cellular …, 2020 - Wiley Online Library
The pathogenesis of non‐alcoholic fatty liver disease (NAFLD) is still not fully understood,
and currently, no effective pharmacotherapy is available. Nuclear receptors (NRs) are …

[HTML][HTML] Tetracyclic and pentacyclic triterpenes with high therapeutic efficiency in wound healing approaches

R Ghiulai, OJ Roşca, DS Antal, M Mioc, A Mioc… - Molecules, 2020 - mdpi.com
Wounds are among the most common skin conditions, displaying a large etiological diversity
and being characterized by different degrees of severity. Wound healing is a complex …

Scutellaria barbata and Hedyotis diffusa herb pair for breast cancer treatment: Potential mechanism based on network pharmacology

TT Ma, GL Zhang, CF Dai, BR Zhang, KX Cao… - Journal of …, 2020 - Elsevier
Abstract Ethnopharmacological relevance The Scutellaria barbata and Hedyotis diffusa (SH)
herb pair is extensively used in Traditional Chinese Medicine for efficacy enhancement in …

[HTML][HTML] Icariin: a potential molecule for treatment of knee osteoarthritis

J Zhang, F Fan, A Liu, C Zhang, Q Li… - Frontiers in …, 2022 - frontiersin.org
Background: Knee osteoarthritis (KOA) is a degenerative disease that develops over time.
Icariin (ICA) has a positive effect on KOA, although the mechanism is unknown. To …

Network pharmacology-based strategy to investigate pharmacological mechanisms of Tinospora sinensis for treatment of Alzheimer's disease

F Zhou, K He, Y Guan, X Yang, Y Chen, M Sun… - Journal of …, 2020 - Elsevier
Abstract Ethnopharmacological relevance Tinospora sinensis (Lour.) Merr. belongs to the
family Menispermaceae. It is called LeZhe and is widely used as a kind of folk medicine …

[HTML][HTML] Growth inhibition and apoptotic effect of pine extract and abietic acid on MCF-7 breast cancer cells via alteration of multiple gene expressions using in vitro …

H Haffez, S Osman, HY Ebrahim, ZA Hassan - Molecules, 2022 - mdpi.com
In vitro anti-proliferative activity of Pinus palustris extract and its purified abietic acid was
assessed against different human cancer cell lines (HepG-2, MCF-7 and HCT-116) …

[HTML][HTML] Bioinformatics and In silico approaches to identify novel biomarkers and key pathways for cancers that are linked to the progression of female infertility: A …

MA Hossain, M Sohel, MH Rahman, MI Hasan… - Plos one, 2023 - journals.plos.org
Despite modern treatment, infertility remains one of the most common gynecologic diseases
causing severe health effects worldwide. The clinical and epidemiological data have shown …

[HTML][HTML] Shenmai injection improves doxorubicin cardiotoxicity via miR-30a/Beclin 1

X Zhang, S Lv, W Zhang, Q Jia, L Wang, Y Ding… - Biomedicine & …, 2021 - Elsevier
Abstract Background Shenmai Injection (SMI) has been widely used in the treatment of
cardiovascular diseases and can reduce side effects when combined with chemotherapy …

Systematic elucidation of the mechanism of quercetin against gastric cancer via network pharmacology approach

L Yang, Z Hu, J Zhu, Q Liang, H Zhou… - BioMed research …, 2020 - Wiley Online Library
This study was aimed at elucidating the potential mechanisms of quercetin in the treatment
of gastric cancer (GC). A network pharmacology approach was used to analyze the targets …