Interferons (IFNs) are the hallmark of the vertebrate antiviral system. Two of the three IFN families identified in higher vertebrates are now known to be important for antiviral defence …
C Langevin, E Aleksejeva, G Passoni, N Palha… - Journal of molecular …, 2013 - Elsevier
Innate immunity constitutes the first line of the host defense after pathogen invasion. Viruses trigger the expression of interferons (IFNs). These master antiviral cytokines induce in turn a …
Y Rao, J Su - Journal of Immunology Research, 2015 - Wiley Online Library
Global fish production from aquaculture has rapidly grown over the past decades, and grass carp shares the largest portion. However, hemorrhagic disease caused by grass carp …
U Ashraf, Y Lu, L Lin, J Yuan… - Journal of General …, 2016 - microbiologyresearch.org
Spring viraemia of carp is an environmentally and economically important disease affecting cyprinids, primarily common carp (Cyprinus carpio). The causative agent of this disease is …
Interferon (IFN) response is the first line of host defense against virus infection. The recent years have witnessed tremendous progress in understanding of fish IFN antiviral response …
Z Gan, SN Chen, B Huang, J Zou… - Reviews in …, 2020 - Wiley Online Library
Interferons (IFN s) have been reported in vertebrates from fish to mammals. To date, two types of IFN s, ie type I and type II IFN s have been reported in a range of fish species in …
SN Chen, PF Zou, P Nie - Immunology, 2017 - Wiley Online Library
Retinoic acid‐inducible gene I (RIG‐I)‐like receptors (RLR s) are found conservatively present in teleost fish. All three members, RIG‐I, MDA 5 and LGP 2, together with the …
A key facet of the innate immune response lays in its ability to recognize and respond to invading microorganisms and cellular disturbances. Through the use of germ-line encoded …