Understanding neutralising antibodies against SARS-CoV-2 and their implications in clinical practice

NYL Pang, ASR Pang, VT Chow, DY Wang - Military Medical Research, 2021 - Springer
SARS-CoV-2 is a newly identified member of the coronavirus family that has caused the
Coronavirus disease 2019 (COVID-19) pandemic. This rapidly evolving and unrelenting …

Does infection with or vaccination against SARS-CoV-2 lead to lasting immunity?

G Milne, T Hames, C Scotton, N Gent… - The Lancet …, 2021 - thelancet.com
Many nations are pursuing the rollout of SARS-CoV-2 vaccines as an exit strategy from
unprecedented COVID-19-related restrictions. However, the success of this strategy relies …

SARS-CoV-2 501Y. V2 escapes neutralization by South African COVID-19 donor plasma

CK Wibmer, F Ayres, T Hermanus, M Madzivhandila… - Nature medicine, 2021 - nature.com
Abstract SARS-CoV-2 501Y. V2 (B. 1.351), a novel lineage of coronavirus causing COVID-
19, contains substitutions in two immunodominant domains of the spike protein. Here, we …

Transmission, infectivity, and neutralization of a spike L452R SARS-CoV-2 variant

X Deng, MA Garcia-Knight, MM Khalid, V Servellita… - Cell, 2021 - cell.com
We identified an emerging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
variant by viral whole-genome sequencing of 2,172 nasal/nasopharyngeal swab samples …

Age-dependent immune response to the Biontech/Pfizer BNT162b2 coronavirus disease 2019 vaccination

L Müller, M Andrée, W Moskorz, I Drexler… - Clinical Infectious …, 2021 - academic.oup.com
Background The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic
has led to the development of various vaccines. Real-life data on immune responses elicited …

Phase 1 randomized trial of a plant-derived virus-like particle vaccine for COVID-19

BJ Ward, P Gobeil, A Séguin, J Atkins, I Boulay… - Nature medicine, 2021 - nature.com
Several severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines are being
deployed, but the global need greatly exceeds the supply, and different formulations might …

An infectivity-enhancing site on the SARS-CoV-2 spike protein targeted by antibodies

Y Liu, WT Soh, J Kishikawa, M Hirose, EE Nakayama… - Cell, 2021 - cell.com
Antibodies against the receptor-binding domain (RBD) of the SARS-CoV-2 spike protein
prevent SARS-CoV-2 infection. However, the effects of antibodies against other spike …

[HTML][HTML] Transmission, infectivity, and antibody neutralization of an emerging SARS-CoV-2 variant in California carrying a L452R spike protein mutation

X Deng, MA Garcia-Knight, MM Khalid, V Servellita… - MedRxiv, 2021 - ncbi.nlm.nih.gov
We identified a novel SARS-CoV-2 variant by viral whole-genome sequencing of 2,172
nasal/nasopharyngeal swab samples from 44 counties in California. Named B. 1.427/B …

Longitudinal analysis of antibody dynamics in COVID-19 convalescents reveals neutralizing responses up to 16 months after infection

Y Yang, M Yang, Y Peng, Y Liang, J Wei, L Xing… - Nature …, 2022 - nature.com
Elucidating the dynamics of the neutralizing antibody (nAb) response in coronavirus disease
2019 (COVID-19) convalescents is crucial in controlling the pandemic and informing …

SARS-CoV-2 seropositivity and subsequent infection risk in healthy young adults: a prospective cohort study

AG Letizia, Y Ge, S Vangeti, C Goforth… - The Lancet …, 2021 - thelancet.com
Background Whether young adults who are infected with SARS-CoV-2 are at risk of
subsequent infection is uncertain. We investigated the risk of subsequent SARS-CoV-2 …