[HTML][HTML] Gene–environment interactions and their impact on human health

SJ Virolainen, A VonHandorf, KCMF Viel… - Genes & …, 2023 - nature.com
The molecular processes underlying human health and disease are highly complex. Often,
genetic and environmental factors contribute to a given disease or phenotype in a non …

[PDF][PDF] Epigenetics of stress-related psychiatric disorders and gene× environment interactions

T Klengel, EB Binder - Neuron, 2015 - cell.com
A deeper understanding of the pathomechanisms leading to stress-related psychiatric
disorders is important for the development of more efficient preventive and therapeutic …

Adiposity amplifies the genetic risk of fatty liver disease conferred by multiple loci

S Stender, J Kozlitina, BG Nordestgaard… - Nature …, 2017 - nature.com
Complex traits arise from the interplay between genetic and environmental factors. The
actions of these factors usually appear to be additive, and few compelling examples of gene …

Stress-related biosocial mechanisms of discrimination and African American health inequities

BJ Goosby, JE Cheadle… - Annual Review of …, 2018 - annualreviews.org
This review describes stress-related biological mechanisms linking interpersonal racism to
life course health trajectories among African Americans. Interpersonal racism, a form of …

“Reports of my death were greatly exaggerated”: Behavior genetics in the postgenomic era

KP Harden - Annual Review of Psychology, 2021 - annualreviews.org
Behavior genetics studies how genetic differences among people contribute to differences in
their psychology and behavior. Here, I describe how the conclusions and methods of …

[HTML][HTML] Childhood maltreatment and DNA methylation: A systematic review

CAM Cecil, Y Zhang, T Nolte - Neuroscience & Biobehavioral Reviews, 2020 - Elsevier
DNA methylation (DNAm)–an epigenetic process that regulates gene expression–may
represent a mechanism for the biological embedding of early traumatic experiences …

The hidden efficacy of interventions: Gene× environment experiments from a differential susceptibility perspective

MJ Bakermans-Kranenburg… - Annual review of …, 2015 - annualreviews.org
The efficacy of interventions might be underestimated or even go undetected as a main
effect when it is hidden in gene-by-environment (G× E) interactions. This review moves …

[HTML][HTML] Interactions between variation in candidate genes and environmental factors in the etiology of schizophrenia and bipolar disorder: a systematic review

B Misiak, F Stramecki, Ł Gawęda, K Prochwicz… - Molecular …, 2018 - Springer
Schizophrenia and bipolar disorder (BD) are complex and multidimensional disorders with
high heritability rates. The contribution of genetic factors to the etiology of these disorders is …

The paradox of intelligence: Heritability and malleability coexist in hidden gene-environment interplay.

B Sauce, LD Matzel - Psychological bulletin, 2018 - psycnet.apa.org
Intelligence can have an extremely high heritability, but also be malleable; a paradox that
has been the source of continuous controversy. Here we attempt to clarify the issue, and …

Neurocognitive outcomes in long-term survivors of childhood acute lymphoblastic leukemia treated on contemporary treatment protocols: A systematic review

YT Cheung, KR Krull - Neuroscience & Biobehavioral Reviews, 2015 - Elsevier
The intensified administration of chemotherapeutic drugs has gradually replaced cranial
radiation therapy (CRT) for the treatment of childhood acute lymphoblastic leukemia (ALL) …