There have been significant advances in our understanding of human autoimmunity that
have led to improvements in classification and diagnosis and, most importantly, research …

Lupus nephritis is an immune complex GN that develops as a frequent complication of SLE.
The pathogenesis of lupus nephritis involves a variety of pathogenic mechanisms. The …

Cell death can be classified according to the morphological appearance of the lethal
process (that may be apoptotic, necrotic, autophagic or associated with mitosis) …

Toll-like receptors (TLRs) have a crucial role in the early detection of pathogen-associated
molecular patterns and the subsequent activation of the adaptive immune response …

Macrophage-inducible C-type lectin (Mincle) is expressed mainly in macrophages and is
induced after exposure to various stimuli and stresses. Here we show that Mincle selectively …

A novel application for non-thermal plasma is the induction of immunogenic cancer cell
death for cancer immunotherapy. Cells undergoing immunogenic death emit danger signals …

Inhibition of programmed cell death is considered to be a major aspect of tumorigenesis.
Indeed, several key oncogenic transcription factors, such as NF-κB and STAT3, exert their …

Systemic lupus erythematosus is a multifactorial autoimmune disease with an as yet
unknown etiopathogenesis. It is widely thought that self-immunization in systemic lupus is …

Rosacea is one of the most common dermatoses of adults. Recent studies have improved
our understanding of the pathophysiology of rosacea. Current concepts suggest that known …

Objective To investigate the activation and recruitment pathways of relevant leukocyte
subsets during the initiation and amplification of cutaneous lupus erythematosus (LE) …