Duplications of human longevity-associated genes across placental mammals
Natural selection has shaped a wide range of lifespans across mammals, with a few long-
lived species showing negligible signs of ageing. Approaches used to elucidate the genetic …
lived species showing negligible signs of ageing. Approaches used to elucidate the genetic …
Pan-primate studies of age and sex
Age and sex have a profound effect on cytosine methylation levels in humans and many
other species. Here we analyzed DNA methylation profiles of 2400 tissues derived from 37 …
other species. Here we analyzed DNA methylation profiles of 2400 tissues derived from 37 …
Aging clocks, entropy, and the limits of age-reversal
AE Tarkhov, KA Denisov, PO Fedichev - BioRxiv, 2022 - biorxiv.org
We analyze aging signatures of DNA methylation and longitudinal electronic medical
records from the UK Biobank datasets and observe that aging is driven by a large number of …
records from the UK Biobank datasets and observe that aging is driven by a large number of …
Social stress is unlikely to play a major role in reproductive suppression of female subordinate naked mole-rats and Damaraland mole-rats
Medger [1] reviewed the mechanisms of reproductive suppression in two eusocial mole-rat
species, the naked (Heterocephalus glaber) and Damaraland mole-rat (Fukomys …
species, the naked (Heterocephalus glaber) and Damaraland mole-rat (Fukomys …
The untapped potential of comparative biology in aging research; insights from the extraordinary-long-lived naked mole-rat
R Buffenstein, VG Amoroso - The Journals of Gerontology …, 2024 - academic.oup.com
The search for solutions to the vagaries of aging have, historically, been akin to searching at
night in the bright light under street lamps by utilizing the few preexisting and well …
night in the bright light under street lamps by utilizing the few preexisting and well …
A cost‐effective blood DNA methylation‐based age estimation method in domestic cats, Tsushima leopard cats (Prionailurus bengalensis euptilurus) and Panthera …
H Qi, QL Lim, K Kinoshita, N Nakajima… - Molecular Ecology …, 2024 - Wiley Online Library
Individual age can be used to design more efficient and suitable management plans in both
in situ and ex situ conservation programmes for targeted wildlife species. DNA methylation is …
in situ and ex situ conservation programmes for targeted wildlife species. DNA methylation is …
Age-associated DNA methylation changes in Xenopus frogs
Age-associated changes in DNA methylation have been characterized across various
animals, but not yet in amphibians, which are of particular interest because they include …
animals, but not yet in amphibians, which are of particular interest because they include …
Age estimation of captive Asian elephants (Elephas maximus) based on DNA methylation: An exploratory analysis using methylation-sensitive high-resolution melting …
K Arai, H Qi, M Inoue-Murayama - Plos one, 2023 - journals.plos.org
Age is an important parameter for bettering the understanding of biodemographic trends—
development, survival, reproduction and environmental effects—critical for conservation …
development, survival, reproduction and environmental effects—critical for conservation …
Divergent age-related methylation patterns in long and short-lived mammals
Age-related changes to cytosine methylation have been extensively characterized across
the mammalian family. Some cytosines that are conserved across mammals exhibit age …
the mammalian family. Some cytosines that are conserved across mammals exhibit age …
[HTML][HTML] Oocyte Aging: A Multifactorial Phenomenon in A Unique Cell
P Kordowitzki, S Graczyk, A Haghani… - Aging and …, 2024 - ncbi.nlm.nih.gov
The oocyte is considered to be the largest cell in mammalian species. Women hoping to
become pregnant face a ticking biological clock. This is becoming increasingly challenging …
become pregnant face a ticking biological clock. This is becoming increasingly challenging …