The brain-heart axis: Integrative analysis of the shared genetic etiology between neuropsychiatric disorders and cardiovascular disease

F Chen, X Dong, Z Yu, Y Zhang, Y Shi - Journal of Affective Disorders, 2024 - Elsevier
Background Multiple observational studies have reported substantial comorbidity between
neuropsychiatric disorders and cardiovascular disease (CVD), but the underlying …

[HTML][HTML] Dissecting the genetic relationship between schizophrenia and cardiovascular disease

RJ Strawbridge, N Graham - American Journal of Psychiatry, 2023 - Am Psychiatric Assoc
Clinicians will be aware of the associations between cardiovascular disease (CVD) and
schizophrenia. The challenge of treating a patient and understanding the impact psychiatric …

[HTML][HTML] Genetic predisposition and antipsychotic treatment effect on metabolic syndrome in schizophrenia: a ten-year follow-up study using the Estonian Biobank

M Alver, S Kasela, L Haring, LB Luitva… - The Lancet Regional …, 2024 - thelancet.com
Background Schizophrenia (SCZ) patients exhibit 30% higher prevalence of metabolic
syndrome (MetS) compared to the general population with its suboptimal management …

[HTML][HTML] A Pilot Interaction Analysis of Gut Microbiota and Peripheral Markers of Aging in Severe Psychiatric Disorders: A Role for Lachnoclostridium?

M Manchia, P Paribello, C Pisanu, D Congiu… - International Journal of …, 2023 - mdpi.com
Excessive predominance of pathological species in the gut microbiota could increase the
production of inflammatory mediators at the gut level and, via modification of the gut–blood …

[HTML][HTML] New Insights Into Psychotic Disorders

NH Kalin - American Journal of Psychiatry, 2023 - Am Psychiatric Assoc
It is estimated that 1.5%–3.5% of the population suffers from some form of affective or
nonaffective psychotic disorder (1). While estimates vary, a relatively recent survey revealed …

[HTML][HTML] Dissecting the genetic overlap between three complex phenotypes with trivariate MiXeR

AA Shadrin, G Hindley, E Hagen, N Parker, M Tesfaye… - medRxiv, 2024 - ncbi.nlm.nih.gov
Comorbidities are an increasing global health challenge. Accumulating evidence suggests
overlapping genetic architectures underlying comorbid complex human traits and disorders …

Management of cardiovascular disease in patients with schizophrenia.

JH Baek - Journal of the Korean Medical Association/Taehan …, 2024 - search.ebscohost.com
Background: Individuals with schizophrenia experience premature mortality by
approximately 15 to 20 years compared to the general population. The most common cause …

Investigating the Comorbidity of Schizophrenia and Metabolic Syndrome Using Real-World Health and Biobank Data

M Alver, S Kasela, L Haring, LB Luitva… - … Research and Fischer … - papers.ssrn.com
Background: Schizophrenia (SCZ) patients exhibit 30% higher prevalence of metabolic
syndrome (MetS) compared to the general population with its suboptimal management …