Congenital syphilis: a review of global epidemiology

LS Gilmour, T Walls - Clinical microbiology reviews, 2023 - Am Soc Microbiol
SUMMARY In 2007, the World Health Organization (WHO) launched a global health
initiative for the elimination of mother-to-child transmission (MTCT) of syphilis. This condition …

Congenital syphilis—an illustrative review

D Sankaran, E Partridge, S Lakshminrusimha - Children, 2023 - mdpi.com
Congenital syphilis is caused by the spirochete, Treponema pallidum, which can be
transmitted from an infected mother to her fetus during pregnancy or by contact with a …

Treponema pallidum genome sequencing from six continents reveals variability in vaccine candidate genes and dominance of Nichols clade strains in Madagascar

NAP Lieberman, MJ Lin, H Xie, L Shrestha… - PLoS neglected …, 2021 - journals.plos.org
In spite of its immutable susceptibility to penicillin, Treponema pallidum (T. pallidum) subsp.
pallidum continues to cause millions of cases of syphilis each year worldwide, resulting in …

Ceftriaxone compared with benzylpenicillin in the treatment of neurosyphilis in France: a retrospective multicentre study

T Bettuzzi, A Jourdes, O Robineau, I Alcaraz… - The Lancet Infectious …, 2021 - thelancet.com
Background Intravenous benzylpenicillin is the gold-standard treatment for neurosyphilis,
but it requires prolonged hospitalisation. Ceftriaxone is a possible alternative treatment, the …

Contact tracing: barriers and facilitators

WM El-Sadr, J Platt, M Bernitz… - American journal of …, 2022 - ajph.aphapublications.org
Contact tracing—the process of identifying, isolating, and managing infected persons and
their contacts—is a recognized public health measure for controlling the transmission of …

The intersection of HIV and syphilis: update on the key considerations in testing and management

M Ren, T Dashwood, S Walmsley - Current HIV/AIDS Reports, 2021 - Springer
Abstract Purpose of Review To highlight recent trends in the epidemiology of HIV and
syphilis, the impact of the COVID epidemic, our approach to care of co-infected patients, and …

The role of engineered materials in mucosal vaccination strategies

B Eshaghi, A Schudel, I Sadeghi, Z Chen… - Nature Reviews …, 2024 - nature.com
Mucosal pathogens, as exemplified by severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), human immunodeficiency virus (HIV) and Mycobacterium tuberculosis, lead …

Global phylogeny of Treponema pallidum lineages reveals recent expansion and spread of contemporary syphilis

MA Beale, M Marks, MJ Cole, MK Lee, R Pitt… - Nature …, 2021 - nature.com
Syphilis, which is caused by the sexually transmitted bacterium Treponema pallidum subsp.
pallidum, has an estimated 6.3 million cases worldwide per annum. In the past ten years, the …

Antimicrobial resistance in sexually transmitted infections

V Tien, C Punjabi, MK Holubar - Journal of travel medicine, 2020 - academic.oup.com
Rationale for review International travel facilitates the spread of drug-resistant infections,
including sexually transmitted infections (STIs). In 2016, the World Health Organization …

Stochastic Petri net model describing the relationship between reported maternal and congenital syphilis cases in Brazil

RAM Valentim, GJP Caldeira-Silva, RD Da Silva… - BMC Medical Informatics …, 2022 - Springer
Introduction Syphilis is a sexually transmitted disease (STD) caused by Treponema pallidum
subspecies pallidum. In 2016, it was declared an epidemic in Brazil due to its high morbidity …