Pancreatic cancer epidemiology, detection, and management

Q Zhang, L Zeng, Y Chen, G Lian… - Gastroenterology …, 2016 - Wiley Online Library
PC (pancreatic cancer) is the fourth most common cause of death due to cancer worldwide.
The incidence and mortality rates have been increasing year by year worldwide, and this …

[HTML][HTML] Selective phytochemicals targeting pancreatic stellate cells as new anti-fibrotic agents for chronic pancreatitis and pancreatic cancer

P Ramakrishnan, WM Loh, SCB Gopinath… - … Pharmaceutica Sinica B, 2020 - Elsevier
Activated pancreatic stellate cells (PSCs) have been widely accepted as a key precursor of
excessive pancreatic fibrosis, which is a crucial hallmark of chronic pancreatitis (CP) and its …

A photonic platform for donor spin qubits in silicon

KJ Morse, RJS Abraham, A DeAbreu, C Bowness… - Science …, 2017 - science.org
Donor spins in silicon are highly competitive qubits for upcoming quantum technologies,
offering complementary metal-oxide semiconductor compatibility, coherence (T 2) times of …

Survival improvement in patients with pancreatic cancer by decade: a period analysis of the SEER database, 1981–2010

H Sun, H Ma, G Hong, H Sun, J Wang - Scientific reports, 2014 - nature.com
Pancreatic cancer (PaCa) is an aggressive malignancy with a high mortality rate and a poor
prognosis. To evaluate treatment outcomes of patients with pancreatic cancer over the past …

[HTML][HTML] Glycolysis promotes the progression of pancreatic cancer and reduces cancer cell sensitivity to gemcitabine

S Dai, Y Peng, Y Zhu, D Xu, F Zhu, W Xu… - Biomedicine & …, 2020 - Elsevier
Previous studies have reported that increased glycolytic activity enhances chemotherapy
resistance in some types of malignancies. However, whether glycolysis influences the …

Pancreatic cancer stem cells: association with cell surface markers, prognosis, resistance, metastasis and treatment

TL Fitzgerald, JA McCubrey - Advances in biological regulation, 2014 - Elsevier
In this review, we will discuss the recent advances in understanding the pancreatic cancer
stem cells. Identification and characterization of pancreatic cancer stem cells may aid our …

Transcriptional repression of SOCS3 mediated by IL-6/STAT3 signaling via DNMT1 promotes pancreatic cancer growth and metastasis

L Huang, B Hu, J Ni, J Wu, W Jiang, C Chen… - Journal of experimental …, 2016 - Springer
Background Previous studies have investigated the sustained aberrantly activated
Interleukin-6 (IL-6)/signal transducer and activator of transcription 3 (STAT3) signaling …

Downregulated miR-98-5p promotes PDAC proliferation and metastasis by reversely regulating MAP4K4

Y Fu, X Liu, Q Chen, T Liu, C Lu, J Yu, Y Miao… - Journal of Experimental & …, 2018 - Springer
Background The aberrant expression of microRNAs (miRNAs) has emerged as important
hallmarks of cancer. However, the molecular mechanisms underlying the differences of …

Long-term survivors of pancreatic cancer: a California population-based study

A Kardosh, DY Lichtensztajn, MA Gubens, PL Kunz… - Pancreas, 2018 - journals.lww.com
Objectives Pancreatic cancer continues to carry a poor prognosis with survival rates that
have had minimal improvement over the past 4 decades. We report a population-based …

Treatment patterns and survival in patients with early‐onset pancreatic cancer

LV Saadat, JF Chou, M Gonen, KC Soares… - Cancer, 2021 - Wiley Online Library
Background Pancreatic cancer is uncommon in patients younger than 50 years, although its
incidence is increasing. This study characterizes treatment utilization for early‐onset …