Cholesterol-rich lipid rafts as platforms for SARS-CoV-2 entry

SN Palacios-Rápalo, LA De Jesus-Gonzalez… - Frontiers in …, 2021 - frontiersin.org
Since its appearance, the Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-2),
the causal agent of Coronavirus Disease 2019 (COVID-19), represents a global problem for …

Metabolic alterations upon SARS-CoV-2 infection and potential therapeutic targets against coronavirus infection

P Chen, M Wu, Y He, B Jiang, ML He - Signal Transduction and …, 2023 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) caused by coronavirus SARS-CoV-2
infection has become a global pandemic due to the high viral transmissibility and …

Diagnostic and prognostic value of serum S100B in sepsis-associated encephalopathy: a systematic review and meta-analysis

J Hu, S Xie, W Li, L Zhang - Frontiers in Immunology, 2023 - frontiersin.org
Background In sepsis, brain dysfunction is known as Sepsis-associated encephalopathy
(SAE), which often results in severe cognitive and neurological sequelae and increases the …

Skeletal muscle in hypoxia and inflammation: insights on the COVID-19 pandemic

FG Di Girolamo, N Fiotti, UG Sisto, A Nunnari… - Frontiers in …, 2022 - frontiersin.org
SARS-CoV-2 infection is often associated with severe inflammation, oxidative stress,
hypoxia and impaired physical activity. These factors all together contribute to muscle …

Beneficial effects of recombinant CER-001 high-density lipoprotein infusion in sepsis: results from a bench to bedside translational research project

A Stasi, M Fiorentino, R Franzin, F Staffieri, S Carparelli… - BMC medicine, 2023 - Springer
Background Sepsis is characterized by a dysregulated immune response and metabolic
alterations, including decreased high-density lipoprotein cholesterol (HDL-C) levels. HDL …

[PDF][PDF] New frontiers in sepsis-induced acute kidney injury and blood purification therapies: The role of polymethylmethacrylate membrane hemofilter

A Stasi, R Franzin, G Caggiano, R Losapio… - Blood …, 2023 - karger.com
Acute kidney injury (AKI) is a common consequence of sepsis with a mortality rate of up to
40%. The pathogenesis of septic AKI is complex and involves several mechanisms leading …

Molecular and cellular mechanisms involved in tissue-specific metabolic modulation by SARS-CoV-2

AAC Santos, LE Rodrigues, AL Alecrim-Zeza… - Frontiers in …, 2022 - frontiersin.org
Coronavirus disease 2019 (COVID-19) is triggered by the SARS-CoV-2, which is able to
infect and cause dysfunction not only in lungs, but also in multiple organs, including central …

Modulation of the cellular microrna landscape: contribution to the protective effects of high-density lipoproteins (HDL)

A Graham - Biology, 2023 - mdpi.com
Simple Summary High-density lipoproteins are often described as the 'good'cholesterol in
the bloodstream, as this complex of lipids (fats) and proteins is known to protect many cells …

[PDF][PDF] Enhancing Immune Protection in Hemodialysis Patients: Role of the Polymethyl Methacrylate Membrane

R Franzin, A Stasi, G Caggiano, E Squiccimarro… - Blood …, 2023 - karger.com
End-stage renal disease (ESRD) is characterized by deep disorders in both innate and
adaptive immune systems that imply unbalance deactivation and immunosuppression. The …

COVID-19 and lipids. The role of lipid disorders and statin use in the prognosis of patients with SARS-CoV-2 infection

S Surma, M Banach, J Lewek - Lipids in health and disease, 2021 - Springer
The global coronavirus disease 2019 (COVID-19) pandemic caused by the SARS-CoV-2
coronavirus started in March 2020. The conclusions from numerous studies indicate that …