Development of nanotechnology-mediated precision radiotherapy for anti-metastasis and radioprotection

Y Pan, W Tang, W Fan, J Zhang, X Chen - Chemical Society Reviews, 2022 - pubs.rsc.org
Radiotherapy (RT), including external beam RT and internal radiation therapy, uses high-
energy ionizing radiation to kill tumor cells. However, ionizing radiation inevitably damages …

Nanodrugs with intrinsic radioprotective exertion: Turning the double‐edged sword into a single‐edged knife

J Guo, Z Zhao, ZF Shang, Z Tang, H Zhu, K Zhang - Exploration, 2023 - Wiley Online Library
Ionizing radiation (IR) poses a growing threat to human health, and thus ideal
radioprotectors with high efficacy and low toxicity still receive widespread attention in …

Recent antioxidative nanomaterials toward wound dressing and disease treatment via ROS scavenging

X He, J Xue, L Shi, Y Kong, Q Zhan, Y Sun, Q Zhang… - Materials Today …, 2022 - Elsevier
Reactive oxygen species (ROS), the main cause of many tissue damage and diseases, are
known to be significantly harmful to various biological components in cells, for example …

An up-to-date review of natural nanoparticles for cancer management

D Ion, AG Niculescu, DN Păduraru, O Andronic… - Pharmaceutics, 2021 - mdpi.com
Cancer represents one of the leading causes of morbidity and mortality worldwide, imposing
an urgent need to develop more efficient treatment alternatives. In this respect, much …

Bacillus subtilis HSY21 can reduce soybean root rot and inhibit the expression of genes related to the pathogenicity of Fusarium oxysporum

S Han, J Chen, Y Zhao, H Cai, C Guo - Pesticide biochemistry and …, 2021 - Elsevier
Soybean root rot occurs globally and seriously affects soybean production. To avoid the
many disadvantages of chemical fungicides, the addition of Bacillus is gradually becoming …

Poloxamer188-based Nanoparticles Improve the Anti-oxidation and Anti-degradation of Curcumin

X Hou, J Liang, X Yang, J Bai, M Yang, N Qiao, Z Hu… - Food Chemistry, 2022 - Elsevier
Curcumin (CUR) is a food additive approved by World Health Organization. But the
shortcomings, such as poor water solubility, easy oxidation and degradation, limit its …

Incorporation of different metal ion for tuning color and enhancing antioxidant activity of curcumin/palygorskite hybrid materials

S Li, B Mu, P Yan, Y Kang, Q Wang, A Wang - Frontiers in Chemistry, 2021 - frontiersin.org
Curcumin is one of the dietary dyes extracted from turmeric and used for prevention and
treatment of various illnesses. However, the low bioavailability and poor stability of curcumin …

Targeted delivery of doxorubicin into tumor cells to decrease the in vivo toxicity of glutathione-sensitive prodrug-poloxamer188-b-polycaprolactone nanoparticles and …

Y Shi, X Hou, SS Yu, X Pan, M Yang, J Hu… - Colloids and Surfaces B …, 2022 - Elsevier
Doxorubicin (DOX) is widely used in the treatment of many tumors, but the dose-dependent
toxicity limits its further application. In this study, a unique strategy was developed to improve …

Overcoming MDR by Associating Doxorubicin and pH-Sensitive PLGA Nanoparticles Containing a Novel Organoselenium Compound—An In Vitro Study

LB Macedo, DR Nogueira-Librelotto, D Mathes… - Pharmaceutics, 2021 - mdpi.com
In this study, we developed PLGA nanoparticles (NPs) as an effective carrier for 5′-Se-
(phenyl)-3-(amino)-thymidine (ACAT-Se), an organoselenium compound, nucleoside …

Recent advances on macromolecular medicinal materials for radioprotection

Y Li, X Wu, Y Pei, Z Wang, C Wang, D Hua - Journal of Drug Delivery …, 2023 - Elsevier
Macromolecular materials have been used in various fields, among which they have played
a significant role in the design of radiation protection drugs so as to prevent the damages of …