[HTML][HTML] Exosome-mediated antigen delivery: unveiling novel strategies in viral infection control and vaccine design

D El Safadi, A Mokhtari, M Krejbich, A Lagrave… - Vaccines, 2024 - mdpi.com
Exosomes are small subtypes of extracellular vesicles (EVs) naturally released by different
types of cells into their environment. Their physiological roles appear to be multiple, yet …

[HTML][HTML] Extracellular Vesicles: Novel Potential Therapeutic Agents in Inflammatory Bowel Diseases

I Mignini, G Piccirilli, F Termite, M Paratore, G Esposto… - Cells, 2023 - mdpi.com
Patients affected by inflammatory bowel diseases (IBD) can nowadays benefit from a
growing number of pharmacological options. However, in moderate-to-severe cases, the …

[HTML][HTML] Delivery Strategies for Colchicine as a Critical Dose Drug: Reducing Toxicity and Enhancing Efficacy

Y Lei, Y Yang, G Yang, A Li, Y Yang, Y Wang, C Gao - Pharmaceutics, 2024 - mdpi.com
Colchicine (COL), a widely used natural drug, has potent anti-inflammatory effects; however,
as a narrow therapeutic index drug, its clinical application is limited by its serious …

[HTML][HTML] HMGB1 Carried by Small Extracellular Vesicles Potentially Plays a Role in Promoting Acquired Middle Ear Cholesteatoma

MW Łuczak, K Dżaman, Ł Zaręba, K Czerwaty… - Diagnostics, 2023 - mdpi.com
Cholesteatoma is a specific medical condition involving the abnormal, non-cancerous
growth of skin-like tissue in the middle ear, potentially leading to a collection of debris and …

A comprehensive insight into the immunomodulatory role of MSCs‐derived exosomes (MSC‐Exos) through modulating pattern‐recognition receptors (PRRs)

MY Alshahrani, SA Jasim… - Cell Biochemistry …, 2024 - Wiley Online Library
Mesenchymal stem cell‐derived exosomes (MSC‐Exos) are emerging as remarkable
agents in the field of immunomodulation with vast potential for diagnosing and treating …

[HTML][HTML] Leveraging high-throughput screening technologies in targeted mRNA delivery

Y Zhang, Z Gao, X Yang, Q Xu, Y Lu - Materials Today Bio, 2024 - Elsevier
Messenger ribonucleic acid (mRNA) has emerged as a promising molecular preventive and
therapeutic approach that opens new avenues for healthcare. Although the use of delivery …

MULTIFUNCTIONAL NANOCARRIERS FOR TARGETED DELIVERY OF THERAPEUTICS.

MK Sharma, G Dharmamoorthy… - … & Cellular Archives, 2023 - search.ebscohost.com
This comprehensive review explores the multifunctional world of nanocarriers for targeted
therapeutic delivery. We delve into critical facets of nanocarrier design, encompassing size …