Development of genistein-loaded gold nanoparticles and their antitumor potential against prostate cancer cell lines

VV Vodnik, M Mojić, U Stamenović, M Otoničar… - Materials Science and …, 2021 - Elsevier
Soy isoflavone genistein (Gen) exerts beneficial effects against prostate cancer cells in vitro
and in vivo. However, its use as a chemoprevention/therapeutic agent is largely limited due …

Dietary factors and supplements influencing prostate-specific antigen (PSA) concentrations in men with prostate cancer and increased cancer risk: An evidence …

MG Grammatikopoulou, K Gkiouras, SΤ Papageorgiou… - Nutrients, 2020 - mdpi.com
The quest for dietary patterns and supplements efficient in down-regulating prostate-specific
antigen (PSA) concentrations among men with prostate cancer (PCa) or increased PCa risk …

Chemopreventive and hepatoprotective effects of genistein via inhibition of oxidative stress and the versican/PDGF/PKC signaling pathway in experimentally induced …

YM El-Far, AE Khodir, ZA Emarah, MA Ebrahim… - Redox …, 2022 - Taylor & Francis
Objective: Genistein is a recognized isoflavone present in soybeans with antioxidant, anti-
inflammatory, antiangiogenic and antitumor activities. This study aimed to test ability of …

Medicinal plants and bioactive natural products as inhibitors of NLRP3 inflammasome

M Bagherniya, H Khedmatgozar… - Phytotherapy …, 2021 - Wiley Online Library
The NLR family, pyrin domain‐containing 3 (NLRP3) inflammasome is a multiprotein
complex that induces caspase‐1 activation and the downstream substrates involved with the …

Current developments in the synthesis of 4-chromanone-derived compounds

EJ Diana, US Kanchana, TV Mathew - Organic & Biomolecular …, 2021 - pubs.rsc.org
The chroman-4-one framework is a significant structural entity that belongs to the class of
oxygen-containing heterocycles. It acts as a major building block in a large class of …

Microbiome dysbiosis in cancer: Exploring therapeutic strategies to counter the disease

VR Sharma, M Singh, V Kumar, M Yadav… - Seminars in cancer …, 2021 - Elsevier
Cancer being a multiplex disease which involves many genomic and physiological
alterations that occur consistently in the cancerous tissue, making the treatment and …

A comprehensive review of the pharmacological importance of dietary flavonoids as hepatoprotective agents

Gajender, A Mazumder, A Sharma… - Evidence‐Based …, 2023 - Wiley Online Library
The liver is a crucial organ that is involved in various kinds of metabolic activity and a very
stable accessory gland for the digestive system. Long‐term or persistent inflammation and …

Genistein—opportunities related to an interesting molecule of natural origin

E Garbiec, J Cielecka-Piontek, M Kowalówka… - Molecules, 2022 - mdpi.com
Nowadays, increasingly more attention is being paid to a holistic approach to health, in
which diet contributes to disease prevention. There is growing interest in functional food that …

[HTML][HTML] Potential of natural products in osteosarcoma treatment: Focus on molecular mechanisms

M Tobeiha, A Rajabi, A Raisi, M Mohajeri… - Biomedicine & …, 2021 - Elsevier
Osteosarcoma is the most frequent type of bone cancer found in children and adolescents,
and commonly arises in the metaphyseal region of tubular long bones. Standard therapeutic …

Heptamethine cyanine dye mediated drug delivery: hype or hope

PJ Choi, TIH Park, E Cooper, M Dragunow… - Bioconjugate …, 2020 - ACS Publications
This review covers the application of heptamethine cyanine dye (HMCD) mediated drug
delivery. A relatively small number of HMCDs possess tumor targeting abilities, and this has …