Epidemiology, pathophysiology, diagnosis and management of chronic right‐sided heart failure and tricuspid regurgitation. A clinical consensus statement of the Heart …

M Adamo, O Chioncel, M Pagnesi… - European journal of …, 2024 - Wiley Online Library
Right‐sided heart failure and tricuspid regurgitation are common and strongly associated
with poor quality of life and an increased risk of heart failure hospitalizations and death …

Pulmonary arterial hypertension: sex matters

JP Dignam, S Sharma, I Stasinopoulos… - British Journal of …, 2024 - Wiley Online Library
Pulmonary arterial hypertension (PAH) is a complex disease of multifactorial origin. While
registries have demonstrated that women are more susceptible to the disease, females with …

Treatment of pulmonary arterial hypertension: recent progress and a look to the future

M Humbert, O Sitbon, C Guignabert… - The Lancet …, 2023 - thelancet.com
Pulmonary arterial hypertension (PAH) is a severe but treatable form of pre-capillary
pulmonary hypertension caused by pulmonary vascular remodelling. As a result of basic …

Elastin stabilization prevents impaired biomechanics in human pulmonary arteries and pulmonary hypertension in rats with left heart disease

MM Kucherenko, P Sang, J Yao, T Gransar… - Nature …, 2023 - nature.com
Pulmonary hypertension worsens outcome in left heart disease. Stiffening of the pulmonary
artery may drive this pathology by increasing right ventricular dysfunction and lung vascular …

[HTML][HTML] Cannabidiol alleviates right ventricular fibrosis by inhibiting the transforming growth factor β pathway in monocrotaline-induced pulmonary hypertension in …

A Krzyżewska, M Baranowska-Kuczko… - … et Biophysica Acta (BBA …, 2023 - Elsevier
Cannabidiol (CBD) is a non-intoxicating compound of Cannabis with anti-fibrotic properties.
Pulmonary hypertension (PH) is a disease that can lead to right ventricular (RV) failure and …

Natural Targeting Potent ROS‐Eliminating Tungsten‐Based Polyoxometalate Nanodots for Efficient Treatment of Pulmonary Hypertension

H Liu, S Wang, Q Chen, X Ge, H Ning… - Advanced …, 2023 - Wiley Online Library
Pulmonary hypertension (PH) is a disease of pulmonary artery stenosis and blockage
caused by abnormal pulmonary artery smooth muscle cells (PASMCs), with high morbidity …

Is low-risk status a surrogate outcome in pulmonary arterial hypertension? An analysis of three randomised trials

BS Blette, J Moutchia, N Al-Naamani… - The Lancet …, 2023 - thelancet.com
Background Targeting short-term improvements in multicomponent risk scores for mortality
in patients with pulmonary arterial hypertension (PAH) could result in improved long-term …

Cardiopulmonary exercise testing during follow-up after acute pulmonary embolism

IT Farmakis, L Valerio, S Barco… - European …, 2023 - Eur Respiratory Soc
Background Cardiopulmonary exercise testing (CPET) may provide prognostically valuable
information during follow-up after pulmonary embolism (PE). Our objective was to …

Chronic thromboembolic pulmonary hypertension: realising the potential of multimodal management

M Delcroix, M de Perrot, X Jaïs, DP Jenkins… - The Lancet …, 2023 - thelancet.com
Chronic thromboembolic pulmonary hypertension (CTEPH) is a rare complication of acute
pulmonary embolism. Important advances have enabled better understanding …

[HTML][HTML] Interleukin-6 and pulmonary hypertension: from physiopathology to therapy

WJ Xu, Q Wu, WN He, S Wang, YL Zhao… - Frontiers in …, 2023 - frontiersin.org
Pulmonary hypertension (PH) is a progressive, pulmonary vascular disease with high
morbidity and mortality. Unfortunately, the pathogenesis of PH is complex and remains …