A disintegrin and a metalloprotease (ADAM) family members have been implicated in many
biological processes. Although it is recognized that recombinant ADAM disintegrin domains …

Neural crest cells have the extraordinary task of building much of the vertebrate body plan,
including the craniofacial cartilage and skeleton, melanocytes, portions of the heart, and the …

Canonical Wnt signaling plays a dominant role in the development of the neural crest (NC),
a highly migratory cell population that generates a vast array of cell types. Canonical Wnt …

Cardiac neural crest (CNC) plays a requisite role during cardiovascular development and
defects in the formation of CNC-derived structures underlie several common forms of human …

Recent evidence indicates, that gap junction forming proteins do not only contribute to
intercellular communication (Kanno and Saffitz in Cardiovasc Pathol 10: 169–177, 2001; …

Directed cell migration often involves at least two types of cell motility that include
multicellular streaming and chain migration. However, what is unclear is how cell contact …

Background: Neural crest cells emerge by delamination from the dorsal neural tube and give
rise to various components of the peripheral nervous system in vertebrate embryos. These …

Formation of neuronal circuits in the head requires the coordinated development of neurons
within the central nervous system (CNS) and neural crest-derived peripheral target tissues …

Adipose tissues constitute an important component of metabolism, the dysfunction of which
can cause obesity and type II diabetes. Here we show that differentiation of white and brown …

Cell migration is essential for proper development of numerous structures derived from
embryonic neural crest cells (NCCs). Although the migratory pathways of NCCs have been …