Indole-chalcone hybrids have burst into prominence as potent weapons in the battle against
pain and inflammation due to their unique features, allowing these ligands to form pivotal …

This review article is a comprehensive and current overview on chalcones, covering their
sources, identification methods, and properties with a particular focus on their applications in …

Chalcones (CHA), based on the 1, 3-diaryl-2-propen-1-one structure, are flavonoids with an
open chain. Wide-ranging biological effects of CHA have been observed, including …

A series of indole-derived methoxylated chalcones were described as anti-dermatophyte
agents. The in vitro antifungal susceptibility testing against different dermatophytes revealed …

Chalcone is a simple and potentially privileged structure in medicinal chemistry with a
diverse repertoire of biological activities, among which cytotoxicity is of particular interest …

Aim: Our objective was to investigate the trypanocidal effect of the chalcone (2 E, 4 E)-1-(2-
hydroxy-3, 4, 6-trimethoxyphenyl)-5-phenylpenta-2, 4-dien-1-one (CPNC). Material & …

In July 2021 we announced a Frontiers Research Topic, hosted by Frontiers in Chemistry,
entitled Advances in green synthesis for drug discovery, as a part of the Green and …

DEET based mosquito repellents were found to be comparatively harmful to the person
suffering from urea cycle disorders such as ornithine transcarbamylase (OTD) deficiency …

The scarce antifungal arsenal, changes in the susceptibility profile of fungal agents, and lack
of adherence to treatment have contributed to the increase of cases of dermatomycoses. In …

Ionic liquids (ILs) are interesting chemical compounds that have a wide range of industrial
and scientific applications. They have extraordinary properties, such as the tunability of …