Multidimensional Functional Profiling of Human Neuropathogenic FOXG1 Alleles in Primary Cultures of Murine Pallial Precursors

S Frisari, M Santo, A Hosseini, M Manzati… - International Journal of …, 2022 - mdpi.com
FOXG1 is an ancient transcription factor gene mastering telencephalic development. A
number of distinct structural FOXG1 mutations lead to the “FOXG1 syndrome”, a complex …

A Framework for the Comparative Assessment of Neuronal Spike Sorting Algorithms towards More Accurate Off‐Line and On‐Line Microelectrode Arrays Data …

G Regalia, S Coelli, E Biffi, G Ferrigno… - Computational …, 2016 - Wiley Online Library
Neuronal spike sorting algorithms are designed to retrieve neuronal network activity on a
single‐cell level from extracellular multiunit recordings with Microelectrode Arrays (MEAs). In …

Open-source tools for processing and analysis of in vitro extracellular neuronal signals

M Mahmud, S Vassanelli - In Vitro Neuronal Networks: From Culturing …, 2019 - Springer
The recent years have seen unprecedented growth in the manufacturing of
neurotechnological tools. The latest technological advancements presented the …

Contrast induced by a static magnetic field for improved detection in nanodiamond fluorescence microscopy

SKR Singam, J Motylewski, A Monaco… - Physical Review …, 2016 - APS
Diamond nanoparticles with negatively charged nitrogen-vacancy (NV) centers are highly
efficient nonblinking emitters that exhibit spin-dependent intensity. An attractive application …

The effect of pharmacological inhibition of Serine Proteases on neuronal networks in vitro

S Van De Vijver, S Missault, J Van Soom… - PeerJ, 2019 - peerj.com
Neurons are embedded in an extracellular matrix (ECM), which functions both as a scaffold
and as a regulator of neuronal function. The ECM is in turn dynamically altered through the …

Brief wide-field photostimuli evoke and modulate oscillatory reverberating activity in cortical networks

R Pulizzi, G Musumeci, C Van den Haute… - Scientific reports, 2016 - nature.com
Cell assemblies manipulation by optogenetics is pivotal to advance neuroscience and
neuroengineering. In in vivo applications, photostimulation often broadly addresses a …

Deep Learning in Biomedical Devices: Perspectives, Applications, and Challenges

SN Nova, MS Rahman, ASMS Hosen - Rhythms in Healthcare, 2022 - Springer
To improve the healthcare management structure with the help of emerging technologies,
biomedical science, and engineering is capturing a huge portion of research. Biomedical …

Author Spotlight: Modular Neuronal Networks for Analyzing Brain Functions

A Hosseini, G Noselli, M Giugliano - JoVE (Journal of Visualized …, 2024 - jove.com
Neuronal cultures have been a reference experimental model for several decades.
However, 3D cell arrangement, spatial constraints on neurite outgrowth, and realistic …

Towards high-resolution brain-chip interface and automated analysis of multichannel neuronal signals

M Mahmud, C Cecchetto, M Maschietto… - 2017 IEEE Region …, 2017 - ieeexplore.ieee.org
To understand brain functions and diagnose brain disorders, scientists have developed
various probing tools and techniques. This development has been facilitated by the rapid …

Single-cell and neuronal network alterations in an in vitro model of fragile X syndrome

A Moskalyuk, S Van De Vijver, P Verstraelen… - Cerebral …, 2020 - academic.oup.com
The Fragile X mental retardation protein (FMRP) is involved in many cellular processes and
it regulates synaptic and network development in neurons. Its absence is known to lead to …