Regenerative medicine harnesses the body's innate capacity for self-repair to restore
malfunctioning tissues and organs. Stem cell therapies represent a key regenerative …

Cardiovascular disease remains the leading cause of mortality worldwide. Cardiomyocytes
are irreversibly lost due to cardiac ischemia secondary to disease. This leads to increased …

Pelvic floor disorders, including pelvic organ prolapse and urinary and fecal incontinence,
affect millions of women globally and represent a major public health concern. Pelvic floor …

Tissue regeneration has been in the spotlight of research for its fascinating nature and
potential applications in human diseases. The trait of regenerative capacity occurs diversely …

The growth of complexity in evolution is a most intriguing phenomenon. Using gene
phylostratigraphy, we showed this growth (as reflected in regulatory mechanisms) in the …

Introduction Dental pulp regeneration is challenging in endodontics. Cellular therapy is an
alternative approach to induce dental pulp regeneration. Mesenchymal stromal cells (MSCs) …

Regeneration enables the regrowth and restoration of missing body parts. It is a common
phenomenon among animals. However, only some species exhibit remarkable regeneration …

The growth of complexity is an unsolved and underappreciated problem. We consider
possible causes of this growth, hypotheses testing, molecular mechanisms, complexity …

Background It is generally accepted that most evolutionary transformations at the phenotype
level are associated either with rearrangements of genomic regulatory elements, which …

Warm-blooded vertebrates regenerate lost limbs and their parts in general much worse than
fishes and amphibians. We previously hypothesized that this reduction in regenerative …