The fragility of statistical findings in distal biceps tendon repairs: a systematic review of randomized controlled trials

MN Megafu, HS Mian, MM Hassan, BO Parsons… - Journal of Shoulder and …, 2023 - Elsevier
Background The purpose of this present study was to perform a fragility analysis to assess
the robustness of randomized controlled trials (RCTs) evaluating the distal biceps tendon …

Randomized controlled trials comparing bone-patellar tendon-bone versus hamstring tendon autografts in anterior cruciate ligament reconstruction surgery are …

KW Lawrence, JO Okewunmi, Z Chakrani… - … : The Journal of …, 2023 - Elsevier
PURPOSE This study aimed to assess the statistical fragility of recently published
randomized controlled trials (RCTs) comparing the use of hamstring tendon (HT) autograft to …

The statistical fragility of orbital fractures: a systematic review of randomized controlled trials

MN Megafu, EC Megafu, JT Nguyen, HS Mian… - Journal of Oral and …, 2023 - Elsevier
Background The P value has often been used as a tool to determine the statistical
significance and evaluate the statistical robustness of study findings in orthopedic literature …

The statistical fragility of outcomes in calcaneus fractures: a systematic review of randomized controlled trials

M Megafu, E Megafu, H Mian, S Singhal, K Nietsch… - The Foot, 2023 - Elsevier
Introduction The purpose of this study was to utilize the fragility index to assess the
robustness of randomized controlled trials (RCTs) evaluating the management of calcaneus …

The fragility of statistical findings in the reverse total shoulder arthroplasty literature: a systematic review of randomized controlled trials

A Yendluri, JJ Chiang, GS Linden, MN Megafu… - Journal of Shoulder and …, 2024 - Elsevier
Background Reverse total shoulder arthroplasty (RTSA) has seen increasing utilization as
an effective intervention for a wide variety of shoulder pathologies. The scope and …

Fragile statistical findings in Randomized controlled trials evaluating Autograft Versus Allograft Use in Anterior Cruciate Ligament Reconstruction: a systematic review

M Megafu, E Megafu, H Mian, S Singhal, A Lee… - … : The Journal of …, 2023 - Elsevier
Purpose The purpose of this study is to analyze the statistical stability of randomized
controlled trials (RCTs) evaluating the surgical management of autografts versus allografts …

The Fragility of Statistical Findings in Cervical Disc Arthroplasty: a Systematic Review of Randomized Controlled Trials

EC Megafu, MN Megafu, JT Nguyen… - Archives of Orthopaedic …, 2024 - Springer
Purpose This study employs both the fragility index (FI) and fragility quotient (FQ) to assess
the level of robustness in the cervical disc arthroplasty (CDA) literature. We hypothesize that …

The fragility index and reverse fragility index of FDA investigational device exemption trials in spinal fusion surgery: a systematic review

JD Proal, AS Moon, B Kwon - European Spine Journal, 2024 - Springer
Purpose FDA investigational device exemption (IDE) studies are considered a gold standard
of assessing safety and efficacy of novel devices through RCTs. The fragility index (FI) has …

The Statistical Fragility of Marrow Stimulation for Cartilage Defects of the Knee: A Systematic Review of Randomized Controlled Trials

A Yendluri, A Alexanian, RR Chari, JJ Corvi… - Cartilage, 2024 - journals.sagepub.com
Objective Marrow stimulation is used to address knee cartilage defects. In this study, we
used the fragility index (FI), reverse fragility index (rFI), and fragility quotient (FQ) to evaluate …

The Statistical Fragility of Tranexamic Acid Use in the Orthopaedic Surgery Literature: A Systematic Review of Randomized Controlled Trials

AN Brown, A Yendluri, KW Lawrence… - JAAOS-Journal of the …, 2024 - journals.lww.com
Methods: PubMed, EMBASE, and MEDLINE were queried for RCTs (2010–present)
reporting dichotomous outcomes with study groups stratified by TXA administration. The FI …